Abstract:The research of traditional Chinese medicine (TCM) is a circle that starts from ‘bed to bench’ then comes back from bench to bed. As a branch of TCM, acupuncture needs to be studied further. In this paper we explore the clinical research of acupuncture through discussing a series trials of acupuncture for constipation. We perform bservational studies as the first step for acupuncture to preliminarily observe its efficacy and safety. Based on the observational study, we carry out randomized controlled trial (RCT) to select the optimal prescription of acupoints, and obtain an acupuncture regimen with the best efficacy and easiest manipulation. Afterwards, we implement a superiority RCT to clarify the therapeutic efficacy of acupuncture by comparing it with placebo needle. Finally, we conduct a non-inferior RCT to explore the clinical application value of acupuncture by comparing it with the ‘gold standard’ if needed.
刘志顺, 吴佳霓. 针刺临床科学研究思路探讨——电针治疗便秘成功案例思考[J]. 科技导报, 2019, 37(15): 63-66.
LIU Zhishun, WU Jiani. Clinical scientific research of acupuncture: deliberation based on a series trials of electro-acupuncture for constipation. Science & Technology Review, 2019, 37(15): 63-66.
[1] 朱中书, 刘方铭, 王玉洁."腹如井, 背如饼" 浅谈[J]. 中国针灸, 2015, 35(4):384. Zhu Zhongshu, Liu Fangming, Wang Yujie. A Brief talk on "Belly as well, back as cake"[J]. Chinese Acupuncture & Moxibustion, 2015, 35(4):384.
[2] 张维, 刘志顺, 王德文. 深刺天枢穴治疗结肠慢转运性便秘15例疗效观察[J]. 新中医, 2004, 36(12):36-37. Zhang Wei, Liu Zhishun, Wang Dewen. Treatment of colonic slow-transport constipation by deep puncture of tianshu point:A clinical observation of 15 cases[J]. New Journal of Traditional Chinese Medicine, 2004, 36(12):36-37.
[3] 刘志顺, 郑成哲, 张维, 等. 深刺天枢治疗老年性便秘近期观察[J]. 中国针灸, 2004, 24(3):155-156. Liu Zhishun, Zheng Chengzhe, Zhangwei, et al. Observation on the short-term therapeutic effect of deep-needling Tianshu (ST 25) on senile constipation[J]. Chinese Acupuncture & Moxibustion, 2004, 24(3):155-156.
[4] 张维, 刘志顺, 李珺. 深刺天枢穴治疗结肠慢转运性便秘30例[J]. 上海针灸杂志, 2005, 24(10):26-27. Zhang Wei, Liu Zhishun, Li Jun. Treatment of 30 patients with colic slow-transport constipation by deep puncture of point Tianshu[J]. Shanghai Journal of Acupuncture and Moxibustion, 2005, 24(10):26-27.
[5] 张维. 深刺天枢穴治疗结肠慢转运性便秘疗效及安全性评价[J]. 中医杂志, 2006, 47(2):105-107. Zhang Wei. Evaluation of therapeutic effect and safety of deep acupuncture at Tianshu (ST25) for treatment of slow transit constipation[J]. Journal of Traditional Chinese Medicine, 2006, 47(2):105-107.
[6] 刘志顺, 段锦绣, 杨德莉, 等. CT直视下个体化深刺天枢操作规范及安全性评价[J]. 中国针灸, 2011, 31(2), 131-133. Liu Zhishun, Duan Jinxiu, Yang Deli, et al. Assessment of the operation standard and safety on the individual deep puncturing at Tianshu (ST25) under CT[J]. Chinese Acupuncture & Moxibustion, 2011, 31(2), 131-133.
[7] Wu J, Liu B, Li N, et al. Effect and safety of deep needling and shallow needling for functional constipation:A multicenter, randomized controlled trial[J]. Medicine (Baltimore), 2014, 93(28):e284.
[8] Liu Z, Yan S, Wu J, et al. Acupuncture for chronic severe functional constipation:A randomized, controlled trial[J]. Annals of Internal Medicine, 2016, 165(11):761-769.
[9] Acupuncture for chronic severe functional constipation[EB/OL].[2019-08-05]. https://annals.altmetric.com/details/11966731/citations.
[10] Acupuncture[EB/OL].[2019-08-05]. https://en.wikipedia.org/wiki/Acupuncture.