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Advances in glaucoma biomechanics research

  • QIAN Xiuqing ,
  • SONG Hongfang ,
  • LIU Zhicheng
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  • Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application;School of Biomedical Engineering, Capital Medical University, Beijing 100069, China

Received date: 2018-05-08

  Revised date: 2018-05-28

  Online published: 2018-07-23

Abstract

Glaucoma ranks the first in the irreparable blindness eye diseases in the world. As the elevated intraocular pressure is the main risk factor of visual impairment, decreasing intraocular pressure is the main treatment of glaucoma at present. Therefore, the biomechanical problem of glaucoma is an important part of the research of pathogenesis, prevention and treatment of glaucoma. The main reason of high intraocular pressure for glaucoma is the increase of outflow resistance of aqueous humor. The increase of intraocular pressure will lead to iris deformation, pupil block, change of flow field of aqueous humor in the anterior chamber, thinning thickness of optic nerve fiber layer and lamina cribrosa, and damage of visual function. Recent advances in glaucoma biomechanics are introduced from aspects of intraocular pressure measurement, measurement of aqueous humor flow, visual function imparied, etc.

Cite this article

QIAN Xiuqing , SONG Hongfang , LIU Zhicheng . Advances in glaucoma biomechanics research[J]. Science & Technology Review, 2018 , 36(13) : 30 -38 . DOI: 10.3981/j.issn.1000-7857.2018.13.004

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