Scientific drilling is an effective way for human beings to explore the interior of the earth, it is also an important means to solve major problems such as resources, disasters and the environment. Scientific drilling projects in the United States, the former Soviet Union, Germany, Japan, Iceland, China and other countries are summarized. The problems in drilling and completion of 10000-meter scientific ultra-deep wells are discussed, including complex geological conditions, high formation temperature, long drilling cycle, difficult well deviation control, etc.. Future applications of geology-engineering integration technology, high-efficiency rock breaking technology, high-temperature drilling fluid technology, and many others in the drilling and completion of 10000 meter scientific ultra deep wells are also prospected.

This paper reviews the research progress of model-based industrial robot error parameter calibration technology to improve the end-effector control accuracy, and summarizes the key problems when industrial robot is applied to high-precision machining and manufacturing, such as incomplete error parameters, high calibration cost and calibration accuracy. Moreover, the paper analyzes the modeling method of error parameter calibration model, end-effector's pose measurement technology, error parameter identification technology and error compensation technology. And the main difficulties of model-based error parameter model calibration technology in dealing with complex calibration tasks are discussed Finally, aimed at some existing problems, a method to efficiently obtain and process the measured error data is proposed and a feasible development direction is also prospected.

Single strand DNA probe-graphene field effect transistor (ssDNA-GFET) nano-biosensor holds great potential in wearable or implantable clinic applications. This paper reviews the development status of ssDNA-GFET, methods on optimizing biomarker sensing performance, detection of biomarkers in human biofluids, and the development status of flexible ssDNA-GFET toward wearable or implantable clinic applications. In the end, the paper demonstrates current limitations of the sensor that hampers its real clinic applications.

Compared with the traditional manufacturing methods of orthopedic insoles, 3D printing orthopedic insoles are intensive and efficient. However, there are still some problems in design, printing, materials and so on, and there is a lack of systematic research review. Based on the manufacturing methods of orthopedic insoles, this paper summarizes the printing technology, printing materials and research status of 3D printing orthopedic insoles, and analyzes the existing problems in the research of 3D printing orthopedic insoles. The future development trend of 3D printing orthopedic insoles is forecasted in terms of the improvement of orthopedic insoles performance and the development of modern science and technology.

To compare the colliders between China and Japan from the perspectives of historical development and running performance and to learn the development experience of Japan and provide references for future technological layout, especially for large research infrastructure planning, this study discovers that the parameters of Chinese collider, which was constructed earlier, are limited by funding, technology, and other factors. Its research field is charm physics, whose energy range is lower than that of B physics. Whereas Japan, which has a foundation in engineering technology, targets at the B physics with richer physics prospects. Both colliders have obtained significant scientific achievements. Japan is more prominent in the research output and the degree of international cooperation is higher. The output of Chinese collider has increased significantly in recent years, and China keeps leading in the research of charm physics.