Abstract:The possible mechanism of Uighur medicine Abnormal Savda Munzip (ASM) on the anti-tumor effects and its influence on tumor cell migration are explored. MTT was applied to determine the cell proliferation of human hepatoma (Bel-7402), human breast carcinoma (BCAP), human cervical cancer (Hela), and human gastric cancer proliferation (BGC-823) after treated with different concentration of ASM (1, 2.5, 5, 10, 20, 50mg/mL) for 48h; Human hepatoma cell line (Bel-7402) was selected for the cell motility study, the cell migration influence on human hepatoma (Bel-7402) were assessed by the wound-healing assay and the Scanning Electron Microscopy (SEM) technique after treated with ASM (5, 10, 20, 50mg/mL) for 48h. ASM produced the cytotoxinic effect on these four type of tumor cells in vitro and all type cells showed the obviously vitro inhibition after treated with ASM (15, 20mg/mL), there were difference inhibited effect among the four type of tumor cells, the results of wound-healing assay with SEM show that the moving ability of Bel-7402 treated with ASM has decreased. It is deduced that ASM might inhibit the ability of proliferation and moving of tumor cell.