Abstract：Objective To observe the immunomodulating effect by formulation of Fu Fang Jian Wei Xiao Shi in mice. Methods 80 healthy female BALB/C mice were administered formulation of Fu Fang Jian Wei Xiao Shi for 30 days with the dose of 0, 0.2, 0.6 and 1.8g/kg body weight, then detected the capacity of lymphocyte proliferation, delayed allergic reaction (DTH), the number of plaque-forming cells, the level of serum HC50 and natural killer cell activity. Results In comparison with the control group, formulation of Fu Fang Jian Wei Xiao Shi could significantly enhance the capacity of the mitogen Concanavalin A(Con A)-induced lymphocyte proliferation, delayed allergic reaction (DTH), the number of plaque-forming cells and natural killer cell activity. Conclusion These results suggest that formulation of Fu Fang Jian Wei Xiao Shi may strengthen the immune function on cellular immunity, humoral immunity and natural killer cell activity.
2010, Vol. 28 
