Overview on interferon in the mucosa immune response of pig mucosal immunity
LIU Lirong1,2, HOU Lidan3, WANG Meng2, LIU Wenjun1,2, LI Jing1,2
1. CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China;
2. Savaid Medical School, University of Chinese Academy of Sciences, Beijing 100049, China;
3. Department of viral biologics, China Institute of Veterinary Drug Control, Beijing 100081, China
Abstract：The animal mucosal immune system serves as the material basis of the immune response, and plays an important role. The vaccine is induced by the mucosal antibody derived from the mucosal immune system, followed by the activated systemic immune response. The interferon acts as a potential mucosal immune adjuvant involved in many biological functions, such as antivirus and immune regulation. This paper reviews the correlation between the mucosal innate immunity and the porcine interferon, focusing on the immunomodulatory roles of the mucosal immune system, the porcine interferon signaling pathway and the immunologic adjuvant, to provide a reference for the development of the porcine interferon as a mucosal immune adjuvant.
刘丽蓉, 侯力丹, 王萌, 刘文军, 李晶. 干扰素在猪黏膜免疫应答中的研究进展[J]. 科技导报, 2018, 36(21): 109-115.
LIU Lirong, HOU Lidan, WANG Meng, LIU Wenjun, LI Jing. Overview on interferon in the mucosa immune response of pig mucosal immunity. Science & Technology Review, 2018, 36(21): 109-115.
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