Abstract：The application of intracranial electrode in the surgery for children with drug-resistant frontal epilepsy with negative MRI is discussed. Retrospective analysis is conducted of 40 cases of children patients in the surgery treatment for drug-resistant frontal epilepsy in our ward between June 2006 and August 2008. Considering the children's seizure manifestations and scalp video electroncephalogram, the intracranial electrode is planted in suspected epileptogenic zones, then based on ECoG and/or cortical stimulation, the real epileptogenic zones are identified. All the patients received surgery treatments to remove epileptogenic zones. The frontal epilepsy was confirmed for all patients. Frontal lobectomy was performed on 12 cases, frontal lobectomy combined with local epileptogenic cortex resection and/or bipolar coagulation of the codex was performed on 8 cases, local epileptogenic cortex resection and/or bipolar coagulation of the codex was performed on 7 cases. Lateral frontal lobectomy combined with local epileptogenic cortex resection and/or bipolar coagulation of the codex was performed on 7 cases. Medial frontal lobectomy combined with local epileptogenic cortex resection and/or bipolar coagulation of the codex was performed on 6 cases (with 3 cases of additional corpus callostomy). There were no severe complication mortality. Patients were followed up for 20 to 36 months. The curative effects were analyzed with Wilson standard in postop, with fineness rate of 80％, 8 cases (20％) were free from seizure, a significant reduction of seizure attack was found in 14 cases (35％), 10 cases (25％) saw a reduction of seizure attack, no change was observed in 8 cases (20％). Therefore, the children frontal epilepsy can be well treated by epileptogenic zones resection, corpus callostomy, bipolar coagulation and frontal lobectomy or by 2 and more methods combined after a precise identification of the epileptogenic zone.
2009, Vol. 27 
