Abstract：Managed Pressure Drilling (MPD) is the key drilling technology for forming with narrow safe density window and being prone to leakage and blowout. The adaptability evaluation technology of MPD is vital to the selection of well and layer and safe operation of MPD. Currently, there is no well-established MPD adaptability evaluation system at home and abroad. The application category and IADC classification about MPD technology are contrasted. The final selection is IADC MPD classification promulgated in 2005, which is a catalog with five kinds of fluid type, six risk level classification, and three kinds of application forms. The geological adaptability evaluation methods of MPD are established. It is the three-step evaluation system, including necessity evaluation, feasibility evaluation, and technical and economic evaluation. The key technologies of MPD geological adaptability evaluation are developed, namely, geological environmental factors describing technology, fine hydraulics model, device matching and optimization, and economic evaluation. Finally, the applications of the technologies in the Block D of Myanmar show that the established classification and geological adaptability evaluation technology has the highly practical value.