医学影像检查可以直观地看到病灶区域,但是却难以判定肿瘤的具体种类和恶化程度。活检是一种有创伤的检查手段,无疑会给病患带来更多的痛苦。磁共振波谱(MRS)是利用波谱的化学位移研究化合物组分和分子结构的一门科学,是医学影像学近年来发展起来的一种新的检查手段。作为一种无创伤研究活体器官组织代谢、生化变化及化合物定量分析方法,磁共振波谱能够反映正常和病理组织的代谢信息和状态,确定组织的性质,被称为“虚拟活检”。本文通过多次实验,不断对解析方案进行修正,最终解析出飞利浦磁共振波谱体素的空间位置信息。根据MR图像的空间位置信息和磁共振波谱体素的空间位置信息,利用可视化工具包VTK,实现了飞利浦磁共振波谱体素与磁共振图像的配准,方便医生精确地了解体素在大脑中的位置,准确地诊断脑肿瘤的类型和级别,为治疗方案的制定和治疗提供参考。

Conventional medical imaging is able to see the nidus area visually; however it is difficult to determine the specific type of tumor and the degree of deterioration. The biopsy is a means of trauma check and undoubtedly will bring patients with much pain. Magnetic Resonance Spectroscopy (MRS) uses magnetic resonance phenomenon and chemical shift to study the existence of compounds or the structure of molecules. Nowadays, MRS is becoming a novel check in medical imaging after years of development. MRS is able to reflect the metabolite distribution of brain tissues without invasion, and is of much importance to diagnose and rank brain tumor. During the MRS check for patients, the location selection of MRS voxel is the key for reflecting the metabolite of the lesion correctly. The spatial information of Philips MRS multi-voxel is correctly understood. Based on the development of Visualization ToolKit (VTK), the registration of MRS multi-voxel and MR image is realized and the convenience for doctors to understand the location of the voxel precisely and know the pattern of the tumor better is provided, and the reference for diagnose and further study is offered. It dramatically reduces the dull work for doctors in practice.