2013年诺贝尔化学奖授予Martin KarpIus，Michael Levitt和Arieh Warshel，以表彰他们对“发展复杂化学体系的多尺度模型”的贡献。3位获奖者的研究建立在理论与计算化学的发展基础之上，而2013年诺贝尔化学奖授予理论化学研究对理论化学工作者而言具有特殊意义，据此本文做了全面阐述。

The 2013 Nobel Prize in Chemistry is awarded to three scientists (Martin Karplus, Michael Levitt and Arieh Warshel) for the dvelopment of multiscale models of complex chemical systems. Their work is based on the development of theoretical and computational chemistry, and the 2013 Nobel Prize in Chemistry is awarded to theoretical chemistry worker has special significance. In this paper, we discuss their works in detail.