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远红外在生物医学临床上的应用及其作用机制

  • 王阳 ,
  • 水珊珊 ,
  • 王霞
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  • 1. 合肥工业大学医学工程学院, 合肥230009;
    2. 合肥工业大学生物与食品工程学院, 合肥230009
王阳,硕士研究生,研究方向为生物医学仪器,电子信箱:331524718@qq.com;

收稿日期: 2014-08-05

  修回日期: 2014-09-02

  网络出版日期: 2014-11-14

基金资助

校企联合技术研发研目(13-240)

Molecular Mechanism of Far- infrared Therapy and Its Applications in Biomedicine

  • WANG Yang ,
  • SHUI Shanshan ,
  • WANG Xia
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  • 1. School of Medical Engineering, Hefei University of Technology, Hefei 230009, China;
    2. School of Biotechnology and Food Engineering, Hefei University of Technology, Hefei 230009, China

Received date: 2014-08-05

  Revised date: 2014-09-02

  Online published: 2014-11-14

摘要

远红外是一种具有强热作用的放射线.作为物理治疗的一种,远红外用于辅助治疗心血管疾病、糖尿病、慢性肾病等多种疾病,表现出良好的临床效果,但是其作用的分子机制尚不清楚.本文从分子信号通路视角,分析远红外与细胞周期、细胞自身保护、第二信使和后转录调控因子等的关系,提出远红外治疗诸多疾病的可能的分子机制,并总结了近年来远红外在生物医学临床中的应用.

本文引用格式

王阳 , 水珊珊 , 王霞 . 远红外在生物医学临床上的应用及其作用机制[J]. 科技导报, 2014 , 32(30) : 80 -84 . DOI: 10.3981/j.issn.1000-7857.2014.30.014

Abstract

Physical therapy is an integrating domain of medicine resorts to physical modalities for the work-up, diagnosis, and treatment of disorders and defects. As a representative physical therapy, far-infrared radiation (FIR), an invisible electromagnetic wave with wavelength ranges 3-1000 μm, has been an adjuvant treatment for various diseases with good clinical effects, including cardiovascular disease, diabetes mellitus, chronic kidney disease; however, the molecular mechanism through which FIR works remains elusive. In the present study, by systematic literature review and text mining, we analyzed the effects of FIR on signaling transduction networks including cell cycle, cellular self-defense, second messages and post-transcriptional regulators. The results showed that the possible mechanisms of FIR therapy were closely associated with the inhibition of growth, invasion and metastasis of cancer cells, increased nitric oxide production and modulation of the expression profiles of some circulating miRNAs and heat shock proteins, and through which, it may be a beneficial compliment to some chronic diseases without any side effects. Finally, we summarized the application of FIR therapy in the field of biomedicine.

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