专题论文

电离辐射的生物效应及健康影响

  • 曹毅 ,
  • 谢文
展开
  • 苏州大学医学部公共卫生学院, 苏州 215123
曹毅,教授,研究方向为辐射毒理学,电子邮箱:yicao@suda.edu.cn;谢文(共同第一作者),硕士研究生,研究方向为辐射毒理学,电子信箱:cheers0725@163.com

收稿日期: 2018-03-20

  修回日期: 2018-07-20

  网络出版日期: 2018-08-27

基金资助

国家自然科学基金项目(K113931113)

The biological effects and health impacts of ionizing radiation

  • CAO Yi ,
  • XIE Wen
Expand
  • School of Public Health, Medical College of Soochow University, Suzhou 215123, China

Received date: 2018-03-20

  Revised date: 2018-07-20

  Online published: 2018-08-27

摘要

人们在日常生活中经常接触辐射,却又因为辐射的不易感知等特性对医疗辐射等低剂量电离辐射产生恐惧心理。介绍了电离辐射的来源、生物效应和对健康的影响,讨论了低剂量电离辐射诱导的兴奋效应和适应性反应。通过引导人们正视电离辐射,并采用适当的防护措施,使电离辐射在人类生活中产生的危害作用降低到人体可接受的水平,可让辐射在医学、工业和科研等领域造福人类。

本文引用格式

曹毅 , 谢文 . 电离辐射的生物效应及健康影响[J]. 科技导报, 2018 , 36(15) : 48 -53 . DOI: 10.3981/j.issn.1000-7857.2018.15.006

Abstract

People are often exposed to radiation in their daily life, but they are also unaware of the low doses of ionizing radiation such as medical radiation because radiation is hard to perceive. In this paper, the source, biological effects and health impacts of ionizing radiation are briefed, and the hormesis and adaptive response of low-dose radiation are discussed. This paper intends to help people to correctly understand ionizing radiation and proposes appropriate protective measures that may reduce the harmful effects of ionizing radiation in human life to some acceptable level for humans, so that radiation can benefit human beings in the fields of medicine, industry and scientific research.

参考文献

[1] 鲁周. 电离辐射危害种种[J]. 现代职业安全, 2007, (2):89. Lu Zhou. Ionizing radiation hazards[J]. Modern Occupational Safety, 2007(2):89.
[2] Kumar V, Vats R P, Pathak P P. Harmful effects of 41 and 202 MHz radiations on some body parts and tissues[J]. Indian Journal of Biochemistry & Biophysics, 2008, 45(4):269-274.
[3] Meredith W J. Harmful effects of ionising radiation[J]. International Journal of Radiation Biology & Related Studies in Physics Chemistry & Medicine, 2009, 2(3):336.
[4] 张梦凡. 低剂量γ射线诱导的淋巴细胞核质桥适应性反应及AKT的作用机制研究[D]. 北京:中国疾病预防控制中心, 2016. Zhang Mengfan. Study on the adaptive response of the lymphocyte nucleus and the mechanism of AKT induced by low-dose gamma-induced lymphocytes[D]. Beijing:Chinese Center For Disease Control, 2016.
[5] Toossi M T B, Dehkordi S A, Sankian M, et al. Effects of adaptive response induced by low-dose ionizing radiation on immune system in spleen lymphocytes of BALB/C mice[J]. Physica Medica, 2016, 32(3):244.
[6] Jiang X, Hong Y, Zhao D, et al. Low dose radiation prevents doxorubicin-induced cardiotoxicity[J]. Oncotarget, 2018, 9(1):332-345.
[7] Stern R G. Medical radiation safety:rational policy, irrational science[J]. American Journal of Medicine, 2012, 125(8):730-731.
[8] 王春燕, 王福合. X射线的发现及其早期研究[J]. 现代物理知识, 2017(1):30-34. Wang Chunyan, Wang Fuhe. Discovery of X-rays and its early research[J]. Modern Physics Knowledge, 2017(1):30-34.
[9] 宋文周, 刘光贤. 浅析放射治疗的发展[J]. 昆明医科大学学报, 2012, (s1):131-133. Song Wenzhou, Liu Guangxian. Analysis of the development of radiation therapy[J]. Journal of Kunming Medical University, 2012, (s1):131-133.
[10] Seymour C, Mothersill C. Low dose radiation effects in the environment:Is the fear or the science irrational?[M]//Radiation Risk Estimates in Normal and Emergency Situations. Springer Netherlands, 2006:169-174.
[11] Scott B R, Di P J. Sparsely ionizing diagnostic and natural background radiations are likely preventing cancer and other genomic-instability-associated diseases[J]. Dose Response, 2007, 5(3):230-255.
[12] Bernal A J, Dolinoy D C, Huang D, et al. Adaptive radiation-induced epigenetic alterations mitigated by antioxidants.[J]. Faseb Journal, 2013, 27(2):665-671.
[13] Tubiana M, Aurengo A. Dose-effect relationship and estimation of the carcinogenic effects of low doses of ionizing radiation[J]. International Journal of Radiation Oncology Biology Physics, 2013, 63(2):317-319.
[14] Wei L, Sugahara T. An introductory overview of the epidemiological study on the population at the high background radiation areas in Yangjiang, China[J]. Journal of Radiation Research, 2000, 41(sl):1-7.
[15] Jr B J. The linear-non threshold (LNT) model as used in radiation protection:An ncrp update[J]. International Journal of Radiation Biology, 2017, 93(10):1-14.
[16] Sies H, Feinendegen L E. Radiation hormesis:The link to nanomolar hydrogen peroxide[J]. Antioxid Redox Signal, 2017, 27(9):596-598.
[17] Nambi K S, Soman S D. Environmental radiation and cancer in India[J]. Health Physics, 1987, 52(5):653-657.
[18] Tubiana M. Dose-effect relationship and estimation of the carcinogenic effects of low doses of ionizing radiation:The joint report of the Académie des Sciences (Paris) and of the Académie Nationale de Médecine[J]. International Journal of Radiation Oncology Biology Physics, 2005, 63(2):317-319.
[19] Ivanov V, Ilyin L, Gorski A, et al. Radiation and epidemiological analysis for solid cancer incidence among nuclear workers who participated in recovery operations following the accident at the Chernobyl NPP[J]. Journal of Radiation Research, 2004, 45(1):41-44.
[20] Jagger J. Natural background radiation and cancer death in Rocky Mountain states and Gulf Coast states[J]. Health Physics, 1998, 75(4):428-430.
[21] Higson D J, Boreham D R, Brooks A L, et al. Effects of low doses of radiation:joint statement from the following participants at the 15th Pacific Basin Nuclear Conference, sessions held in Sydney, Australia, Wednesday 18 October 2006[J]. Dose-Response, 2007, 5(4):259-262.
[22] Olivieri G, Bodycote J, Wolff S. Adaptive response of human lymphocytes to low concentrations of radioactive thymidine[J]. Science, 1984, 223(4636):594-597.
文章导航

/