To analyze the correlation of the preoperative serum biomarkers and the body mass index with the preoperative knee scoring and the pre/post-operative pain scores for patients with ACL rupture, the preoperative data of the serum bio-markers and the body mass index are collected from 52 patients, to make the correlation analysis for the preoperative knee scoring and the pre/post-operative pain scores by Shapiro-Wilk and Spearman tests. Positive correlations are found between the preoperative blood uric acid level and the pre/post-operative pain scores, between the body mass index and the preoperative Lysholm score and the postoperative pain score, and between the creatine kinase level and the postoperative pain score.
[1] Catterall J B, Stabler T V, Flannery C R, et al. Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254)[J]. Arthritis Research & Therapy, 2010, 12(6):R229.
[2] 王健, 王永健, 王海军, 等. 长病程前交叉韧带损伤后膝关节继发改变研究[J]. 中国运动医学杂志, 2019(4):276-280.
[3] Kaplan D J, Cuellar V G, Jazrawi L M, et al. Biomarker changes in anterior cruciate ligament-deficient knees compared with healthy controls[J]. Arthroscopy:The Journal of Arthroscopic & Related Surgery, 2017, 33(5):1053-1061.
[4] Harkey M S, Luc B A, Golightly Y M, et al. Osteoarthritis-related biomarkers following anterior cruciate ligament injury and reconstruction:A systematic review[J]. Osteoarthritis and Cartilage, 2015, 23(1):1-12.
[5] Konstari S, Sares-Jäske L, Heliövaara M, et al. Dietary magnesium intake, serum high sensitivity C-reactive protein and the risk of incident knee osteoarthritis leading to hospitalization-A cohort study of 4,953 Finns[J]. PloS One, 2019, 14(3):e0214064.
[6] Zeng C, Li H, Wei J, et al. Association between dietary magnesium intake and radiographic knee osteoarthritis[J]. PLoS One, 2015, 10(5):e0127666.
[7] Mao Y, Xu W, Xie Z, et al. Association of irisin and CRP levels with the radiographic severity of knee osteoarthritis[J]. Genetic Testing and Molecular Biomarkers, 2016, 20(2):86-89.
[8] Teng G G, Leung Y Y, Ang L W, et al. Gout and risk of knee replacement for severe knee osteoarthritis in the Singapore Chinese Health Study[J]. Osteoarthritis and Cartilage, 2017, 25(12):1962-1968.
[9] Guss J D, Ziemian S N, Luna M, et al. The effects of metabolic syndrome, obesity, and the gut microbiome on load-induced osteoarthritis[J]. Osteoarthritis and Cartilage, 2019, 27(1):129-139.
[10] Torjussen J, Bahr R. Injuries among elite snowboarders (FIS snowboard world cup)[J]. British Journal of Sports Medicine, 2006, 40(3):230-234.
[11] Bere T, Flørenes T W, Nordsletten L, et al. Sex differences in the risk of injury in World Cup alpine skiers:A 6-year cohort study[J]. British Journal of Sports Medicine, 2014, 48(1):36-40.
[12] Spörri J, Kröll J, Gilgien M, et al. How to prevent injuries in alpine ski racing:What do we know and where do we go from here?[J]. Sports Medicine, 2017, 47(4):599-614.
[13] Weir C B, Jan A. BMI classification percentile and cut off points[EB/OL]. (2019-12-07)[2019-12-20]. https://www.ncbi.nlm.nih.gov/books/NBK541070/.
[14] Zheng H, Chen C. Body mass index and risk of knee osteoarthritis:Systematic review and meta-analysis of prospective studies[J]. BMJ Open, 2015, 5(12):e007568.
[15] Bodkin S G, Werner B C, Slater L V, et al. Post-traumatic osteoarthritis diagnosed within 5 years following ACL reconstruction[J]. Knee Surgery, Sports Traumatology, Arthroscopy, 2019, doi:10.1007/s00167-019-05461-y.
[16] Harris K, Driban J B, Sitler M R, et al. Five-year clinical outcomes of a randomized trial of anterior cruciate ligament treatment strategies:An evidence-based practice paper[J]. Journal of Athletic Training, 2015, 50(1):110-112.
[17] DiSilvestro K J, Jauregui J J, Glazier E, et al. Outcomes of anterior cruciate ligament reconstruction in obese and overweight patients:A systematic review[J]. Clinical Journal of Sport Medicine, 2019, 29(4):257-261.
[18] Meuffels D E, Favejee M M, Vissers M M, et al. Ten year follow-up study comparing conservative versus operative treatment of anterior cruciate ligament ruptures. A matched-pair analysis of high level athletes[J]. British Journal of Sports Medicine, 2009, 43(5):347-351.
[19] Neuman P, Englund M, Kostogiannis I, et al. Prevalence of tibiofemoral osteoarthritis 15 years after nonoperative treatment of anterior cruciate ligament injury:A prospective cohort study[J]. The American Journal of Sports Medicine, 2008, 36(9):1717-1725.
[20] Ganguly A. Levels of C-reactive protein, creatine kinase-muscle and aldolase A are suitable biomarkers to detect the risk factors for osteoarthritic disorders:A novel diagnostic protocol[J]. Caspian Journal of Internal Medicine, 2019, 10(1):25.
[21] Mittl G S, Zuckerman J D. The unique macroscopic appearance of gouty arthritis of the knee[J]. Bulletin of the NYU Hospital for Joint Diseases, 2015, 73(3):210.
[22] 钱凯, 张筠雩, 李春梅, 等. 血尿酸不高的急性痛风患者血清中IL-6, IL-1β和炎症指标的表达水平及临床意义分析[J]. 标记免疫分析与临床, 2018, 25(2):183-185.
[23] Neogi T, Krasnokutsky S, Pillinger M H. Urate and osteoarthritis:Evidence for a reciprocal relationship[J]. Joint Bone Spine, 2019, 86(5):576-582.
[24] Smith J W, Martins T B, Gopez E, et al. Significance of C-reactive protein in osteoarthritis and total knee arthroplasty outcomes[J]. Therapeutic Advances in Musculoskeletal Disease, 2012, 4(5):315-325.