专题:儿童青少年心理健康

铁缺乏相关儿童睡眠障碍研究进展

  • 孙一凡 ,
  • 李桃美 ,
  • 张海鹏 ,
  • 时媛 ,
  • 唐向东
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  • 四川大学华西医院睡眠医学中心, 成都 610041
孙一凡,硕士,研究方向为睡眠医学,电子信箱:1014585663@qq.com

收稿日期: 2020-09-27

  修回日期: 2021-02-18

  网络出版日期: 2021-10-09

基金资助

国家自然科学基金项目(81530002)

Review of studies of iron deficiency-related sleep disorders in children

  • SUN Yifan ,
  • LI Taomei ,
  • ZHANG Haipeng ,
  • SHI Yuan ,
  • TANG Xiangdong
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  • Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China

Received date: 2020-09-27

  Revised date: 2021-02-18

  Online published: 2021-10-09

摘要

铁缺乏是儿童最常见的微量营养素缺乏症。中国缺铁儿童数量众多,尤其婴幼儿是铁缺乏的高发人群;睡眠是机体发育、修复、调整的重要环节,良好的睡眠对发育中的个体尤其重要。近年来,研究发现铁缺乏可能与几类常见的儿童睡眠障碍有关。从临床特点、病理机制和补铁治疗等方面,回顾了国内外铁缺乏相关儿童睡眠障碍的研究前沿成果。研究结果表明,铁缺乏可能通过引起神经递质紊乱,影响神经髓鞘和树突的形成等途径,导致缺铁儿童睡眠中异常活动增多,补铁治疗被发现可改善部分患儿的睡眠运动症状。

本文引用格式

孙一凡 , 李桃美 , 张海鹏 , 时媛 , 唐向东 . 铁缺乏相关儿童睡眠障碍研究进展[J]. 科技导报, 2021 , 39(18) : 57 -64 . DOI: 10.3981/j.issn.1000-7857.2021.18.008

Abstract

The iron deficiency is the most common micro-nutrient deficiency in children, with a large number of children falling victims in China, especially infants, which are at a very high risk. The sleep plays an important part in the body's development, repair and adjustment, and is particularly important in the developing stage. It is revealed by increasing number of studies that the iron deficiency is probably associated with several common sleep disorders in children. This paper reviews the cutting-edge studies of iron deficiency-related sleep disorders in children, including the clinical characteristics, the possible pathological mechanism and the iron supplement therapy. The iron deficiency may lead to increased abnormal activities during sleep in children by causing disorders of neurotransmitters, altering the processes of the myelination and the formation of dendrites. The iron supplementation therapy was reported to improve the symptoms of sleep movements in some children.

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