微马达和微生物前沿交叉领域研究进展

王建敏; 林岚; 孔亮盛

doi:10.3981/j.issn.1000-7857.2023.02.010

科技导报 >

2023 , Vol. 41 >Issue 2: 89 - 95

DOI: https://doi.org/10.3981/j.issn.1000-7857.2023.02.010

综述

微马达和微生物前沿交叉领域研究进展

王建敏 ,
林岚 ,
孔亮盛

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1. 重庆医科大学附属永川医院检验科, 重庆 402160;
2. 重庆大学附属三峡医院医学检验科, 重庆 404100

王建敏,主管技师,研究方向为分子诊断及生物分析化学,电子信箱:wangjianmin099@163.com

收稿日期: 2021-09-15

修回日期: 2022-05-14

网络出版日期: 2023-02-10

基金资助

重庆市科卫联合医学科研项目（2018MSXM138）；临床检验诊断学教育部重点实验室开放研究课题（KF202006）；重庆大学附属三峡医院科研人才专项（2022YJKYXM-038）；重庆医科大学附属永川医院院级科研项目（YJLC201718）

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Developments of the advanced crossing of micromotors and microorganisms

WANG Jianmin ,
LIN Lan ,
KONG Liangsheng

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1. Department of Clinical Laboratory, Yongchuan Hospital of Chongqing Medical University, Chongqing 402160, China;
2. Department of Clinical Laboratory, Chongqing University Three Gorges Hospital, Chongqing 404100, China

Received date: 2021-09-15

Revised date: 2022-05-14

Online published: 2023-02-10

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摘要

微马达是一种可将不同形式的能量转化为动能进而实现自主运动的微型工具。近年来，该研究逐渐拓宽至微马达与微生物交叉领域。总结了微生物马达的制备、微马达在微生物的检测及体内应用等方面的研究进展。微生物的识别机制及生物相容性与微马达的自主运动能力互为补充，因此微生物马达的出现既为微马达的在体应用提供了新思路，也为微生物的检验提供了新方法。目前，受制于制备方法相对落后、运动并非完全可控、体内降解困难等限制因素，相较于其他类型的微马达，微生物马达的研究仍处于相对原始的阶段。提出了对马达新材料的研发和驱动方法的优化将会有效解决问题并赋予微生物马达更加广泛的应用前景。

关键词： 微生物马达; 微生物检测; 杀菌

本文引用格式

王建敏 , 林岚 , 孔亮盛 . 微马达和微生物前沿交叉领域研究进展[J]. 科技导报, 2023 , 41(2) : 89 -95 . DOI: 10.3981/j.issn.1000-7857.2023.02.010

Abstract

As a kind of micro-tools which could convert other kinds of energies into kinetic energy thus propel themselves moving forward, the researches of micromotors have been gradually broadened to the crossing filed with microorganisms, such as the preparation of the microorganic-micromotors (MMs) with their applications in the detections of microorganisms, sterilization and drug delivery in vivo. The sensing mechanism and biocompatibility of microorganisms were complementary to the autonomous movement of micromotors, thus their combination provided new ideas and methods for the applications of micromotors and detections for microorganisms. However, limited by the finite preparation methods, uncontrollable motion and difficult degradation, the researches of MMs were more primitive when comparing with others, while the development of new materials and the optimization of driving methods will effectively solve the problems and develop wider application prospect for MMs.

Key words： microorganic-micromotors; detection of microorganisms; sterilization

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