卫生部药品标准中药成方制剂中含反药药对成方制剂收载情况与分析

王 茜;钟赣生;刘 佳;欧丽娜;陈绍红

doi:10.3981/j.issn.1000-7857.2011.02.010

科技导报 >

2011 , Vol. 29 >Issue 11-02: 59 - 64

DOI: https://doi.org/10.3981/j.issn.1000-7857.2011.02.010

研究论文

卫生部药品标准中药成方制剂中含反药药对成方制剂收载情况与分析

王茜;钟赣生;刘佳;欧丽娜;陈绍红

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北京中医药大学基础医学院，北京 100029

收稿日期: 2010-11-05

修回日期: 2010-12-27

网络出版日期: 2011-01-18

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Analysis of the Chinese Patent Medicines with Incompatible Herbs in Drug Standard of Ministry of Public Health

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Received date: 2010-11-05

Revised date: 2010-12-27

Online published: 2011-01-18

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摘要

“十八反”、“十九畏”作为中医药领域传统的配伍禁忌，一直沿用至今，但由于临床不乏反药同用治疗某些疾病突显奇效的病案，其是否确属绝对配伍禁忌，是众多学者及临床医生关注的热点问题。《中华人民共和国卫生部药品标准·中药成方制剂》是卫生部为解决中药材品种混乱问题，保证人民用药安全有效，颁布的具有权威性的法定标准。据统计，其1~20册共收载成方制剂4052个品种，其中含反药配伍的成方制剂65个，包括含“十八反”药对的品种43个，含“十九畏”药对的品种25个，既含“十八反”又含“十九畏”药对的品种3个。经分析可知，该标准含反药药对的成方中以乌头类与半夏、官桂与赤石脂配伍使用为多；其临床应用特点，含“十八反”药对的成方主要用于风湿痹病、跌打损伤，剂型以丸剂、膏药、橡胶膏剂为主，口服与外用比例相当；含“十九畏”药对的成方主要用于月经不调，以丸剂口服为主。在处方药味数方面，含反药药对的成方以16~30味的处方较多。

关键词： 卫生部药品标准; 中药成方制剂; 十八反; 十九畏

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王茜;钟赣生;刘佳;欧丽娜;陈绍红 . 卫生部药品标准中药成方制剂中含反药药对成方制剂收载情况与分析[J]. 科技导报, 2011 , 29(11-02) : 59 -64 . DOI: 10.3981/j.issn.1000-7857.2011.02.010

Abstract

Eighteen incompatible herbs and nineteen herbs of mutual antagonism, the incompatibility between the traditional Chinese medicines has had the history of thousands of years so far; whether eighteen incompatible herbs and nineteen herbs of mutual antagonism are incompatibility or not has become one of the hot spot of academia right now. "Drug Standard of Ministry of Public Health of the People's Republic of China-Chinese Patent Medicine" is an authoritative and statutory standard to identify the quality and variety of herbs and ensure safe and effective administration by Ministry of Public Health. According to statistics, there are 4052 kinds of Chinese Patent Medicines (CPMs) in "Drug Standard of Ministry of Public Health of the Peoples Republic of China-Chinese Patent Medicine", in which 43 CPMs contain eighteen incompatible herbs, 25 CPMs contain nineteen herbs of mutual antagonism, and three CPMs contain both eighteen incompatible herbs and nineteen herbs of mutual antagonism. The CPMs containing eighteen incompatible herbs and nineteen herbs of mutual antagonism are analyzed to offer some elicitation for promoting rational drug use in the clinic.

Key words： Drug Standard of Ministry of Public Health; Chinese Patent Medicines; eighteen incompatible herbs; nineteen herbs of mutual antagonism

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