为了建立2型糖尿病维医异常体液分型诊断标准,以非疾病诊断临床相关信息为依据,对诊断明确的305例2型糖尿病患者进行了量化诊断入选项专家咨询研究。入选的证候要素进行多分类Logistic回归分析、共线性诊断及主成分分析,使用主成分改进的多分类Logistic回归分析方法确立各证候要素对证候的贡献度,根据OR值区分2型糖尿病各异常体液主症、次症。研究结果显示,2型糖尿病异常黑胆质型主症为心神不宁,口干,舌苔为薄白苔,舌质紫暗,口味苦涩;次症为唇色青紫,舌体胖、短,小便青色。2型糖尿病异常血液质型主症为皮肤较热,脉象粗、有力,目光乏神,结膜稍红;次症为舌质色暗、舌苔光滑,面色发红,皮肤略粗。2型糖尿病异常黏液质型主症为唇色淡白,精神疲惫,口黏,舌苔白腻;次症为面色晄白,结膜发白,睡眠较多,脉象沉、缓。2型糖尿病异常胆液质型主症为心烦,脉象细,面色黄白,唇色淡不润,结膜发黄,皮肤较热;次症为面色无华,目光乏神,舌苔色黄,皮肤粗糙。经过对量化诊断入选项专家咨询所得到的临床信息的统计分析,认为研究结果与临床实际比较符合,可靠性高。由此得出结论:2型糖尿病维医异常体液分型诊断标准的建立为开展2型糖尿病维医临床疗效标准研究奠定了基础,同时此标准的建立也为方法学提供了参考。
To set up abnormal Hilit typing quantization diagnostic criteria of Uighur medicine for the type 2 diabetes patients, based on the free disease clinical diagnostic information, 305 type 2 diabetes patients were selected in the study of quantifying diagnosis specialist counseling. Selected factors were analyzed by the modified multi-categorization logistic regression analysis to determine the symptom-complex factor dedication degree and the symptom-complex factor main and subsequent symptoms of the abnormal hilit of type 2 diabetes through OR values. As a result, the meaningful symptoms were found in all the abnormal hilit syndromes according to the OR values. It is shown that the chief symptoms of the abnormal savda type diabetes are nervousness in mind, dry mouth, thin white tongue coating, dark purple tongue and, bitter taste. The subsequent symptoms are cyanotic lips, fat, short tongue, thin and pale urine. The chief symptoms of the abnormal kan type diabetes are hot skin, thick, strong pulse, lack of eye expression and reddish conjunctiva. The subsequent symptoms are dark red tongue, smooth tongue coating, reddish complexion and slightly rough skin. The chief symptoms of abnormal balgham type diabetes are pale lips, weariness in mind, sticky mouth, white and greasy tongue coating. Subsequent symptoms are pale complexion, whitish conjunctiva, lack of sleep, and deep, slow pulse. The chief symptoms of abnormal sapra type diabetes are acute mind and excessive anger, yellowish complexion, pale lips, yellowish conjunctiva, and hot skin. Subsequent symptoms are dim complexion, lack of eye expression, yellow face color and rough skin. The features of excess syndromes of the four abnormal hilit syndromes identified by the Delphi method are in line with clinical practice. The establishment of the standards would provide a ground for developing the clinical effect standards for the traditional Uighur medicine and at the same time, a methodological reference for the establishment of the related standards.