“相反”药物配伍应用自古不乏其例,一味遵循“十八反”,是否制约着治疗用药,使一些疑难杂症无法治愈,使中医药“相反相激”的快捷疗效无法体现？而全盘否定,是否又会误用后引起中毒、甚至死亡而涂炭生灵？这些均是悬而未决的问题.鉴于临床应用中,“相反”药物配伍多用于特定的病理条件下,本文提出在临床应用的基础上,选择含有反药配伍的经方,针对其主治病证病理条件下“相反”药物配伍的不同条件进行研究,从而挖掘基于临床应用的中药“十八反”宜忌条件及配伍关系,对完善中药配伍理论和指导临床“相反”药物配伍具有重要的理论价值和现实意义.

The examples of compatibility use of incompatible medicaments are abound. Does the practice of complying with eighteen incompatible medicaments affect the curative effect? Whether will the incompatible medicaments necessarily cause toxic reactions even death? They are issues open to discussion. The compatibility of incompatible medicaments is usually considered in specified pathological conditions clinically. This paper suggests that we can study the classical Prescriptions that include incompatible medicaments, to sum up various kinds of compatibility conditions in the specified pathological conditions based on the clinical applications. These studies are of theoretical and practical significance to guide reasonable applications of incompatible medicaments and to perfect the compatible theory of TCM.