专题论文

干细胞与再生医学发展前瞻

  • 刘晶 ,
  • 曹尚涛 ,
  • 蔡景蕾 ,
  • 裴端卿
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  • 中国科学院广州生物医药与健康研究院, 中国科学院再生生物学重点实验室, 广东省干细胞与再生医学重点实验室, 华南干细胞与再生医学研究所, 广州 510530
刘晶,副研究员,研究方向为干细胞及诱导多能性干细胞,电子信箱:liu_jing@gibh.ac.cn

收稿日期: 2016-10-14

  修回日期: 2016-10-19

  网络出版日期: 2016-11-05

Perspective of stem cell and regenerative medicine

  • LIU Jing ,
  • CAO Shangtao ,
  • CAI Jinglei ,
  • PEI Duanqing
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  • Key Laboratory of Regenerative Biology;Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine;South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China

Received date: 2016-10-14

  Revised date: 2016-10-19

  Online published: 2016-11-05

摘要

干细胞与再生医学是当今生命科学领域研究的前沿与热点。近年来,涌现出一系列突破性的研究成果,将干细胞研究推向新的历史阶段,为再生医学的发展带来深刻变革。本文分析体内外不同来源的干细胞在再生医学的治疗应用、小分子化合物在细胞命运转变机理研究和功能性细胞获取方面的研究现状与前景,讨论了干细胞与再生医学在临床治疗应用的安全性与规范性。

本文引用格式

刘晶 , 曹尚涛 , 蔡景蕾 , 裴端卿 . 干细胞与再生医学发展前瞻[J]. 科技导报, 2016 , 34(20) : 25 -33 . DOI: 10.3981/j.issn.1000-7857.2016.20.004

Abstract

Recently, a series of breakthroughs in stem cell and regenerative medicine, as the frontier and the hotspot of life sciences, brings numbers of revolutionary changes into the medical development. In this paper, we mainly summarize and analyze the current progresses and perspectives of the applications of stem cells from distinct resources in vitro and in vivo for the regenerative treatment and the roles of small molecules in the mechanisms involved in the cell fate transition and the functional cells obtained in vitro. Meanwhile, the safety and the regulation of the applications of the stem cell and regenerative medicine in the clinical therapy are discussed, to provide some food for thought for reasonable arrangements and plots in this field.

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