Differential value of platelet distribution width and serum albumin level between thyroid cancer and benign thyroid nodules

LI Juan; ZHANG Xuehui; FENG Shuangshuang; SHEN Jinfu; XIE Shuyong; NIU Min

doi:10.3981/j.issn.1000-7857.2021.07.008

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Science & Technology Review ›› 2021, Vol. 39 ›› Issue (7) : 79-84. DOI: 10.3981/j.issn.1000-7857.2021.07.008

Differential value of platelet distribution width and serum albumin level between thyroid cancer and benign thyroid nodules

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Fuyang People's Hospital, Fuyang 236000, China

Abstract

In order to analyze the differential values of platelet distribution width (PDW), mean platelet volumes (MPVs), and serum albumin (ALB) levels in thyroid cancer and benign thyroid nodules, 237 patients with thyroid cancer diagnosed in the hospital from Jan. 2016 to Sept. 2020 were selected as the study group, and 237 patients with benign thyroid nodules were selected as the control group. The PDWs, ALBs and MPVs of the two groups were observed and the clinical values of predicting thyroid cancer were evaluated. Results show that MPV and ALB of the study group are lower and PDW is higher than those of the control group, and the differences are statistically significant (P<0.05). PDW, MPV,ALB in the diagnosis of thyroid cancer AUC are not statistically significant (P > 0.05). The specificity of PDW, MPV and ALB is higher than that of PDW, MPV and ALB alone, and the sensitivity of PDW, MPV and ALB is higher than that of PDW, MPV and ALB alone. Therefore, PDW, MPV and ALB are of moderate clinical value in the differential diagnosis of benign and malignant thyroid nodules. Different combination of the three indexes is helpful to the diagnosis or exclusion of thyroid cancer.

Key words

thyroid cancer / thyroid nodules / platelet distribution width / albumin / mean platelet volum

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LI Juan, ZHANG Xuehui, FENG Shuangshuang, SHEN Jinfu, XIE Shuyong, NIU Min. Differential value of platelet distribution width and serum albumin level between thyroid cancer and benign thyroid nodules[J]. Science & Technology Review, 2021, 39(7): 79-84 https://doi.org/10.3981/j.issn.1000-7857.2021.07.008

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