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| Correlation Analysis of Plasma Fatty Acid Levels in Patients with Tumor and Abnormal Savda in Uyghur Medicine |
| MAMTIMIN Batur1, SUN Feng2, KELIMU Alimujiang3, KONG Bin1, GONG Can1, UPUR Halmurat4 |
1. College of Pharmacy, Xinjiang Medical University, Urumqi 830011, China;
2. The Fourth Affiliated Hospital, Xinjiang Medical University, Urumqi 830011, China;
3. Department of Neurosurgery, Shanghai East Hospital Affiliated to Tongji University, Shanghai 200120, China;
4. College of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830011, China |
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Abstract: To investigate the plasma fatty acid metabolism of different cancer patients with abnormal Savda in Uyghur medicine and analyze its common features, the plasma fatty acid concentration was tested by the gas chromatography (GC) from 122 cases of cancer patients with abnormal Savda including 25 cases of esophageal cancer, 20 cases of colorectal cancer, 33 cases of lung cancer, 20 cases of breast cancer and 24 cases of gastric cancer, and 35 healthy volunteers as a control group. The spectral profiles were subjected to a t-test for statistical significance. The results show that compared to the healthy group, the patients of esophageal cancer, colorectal cancer, lung cancer, breast cancer and gastric cancer with abnormal Savda suffer a high concentration of myristic acid; the patients of esophageal cancer, lung cancer, breast cancer and gastric cancer with abnormal Savda suffer a high concentration of palm acid; the patients of colorectal cancer, lung cancer and breast cancer with abnormal Savda suffer a high concentration of palmitic acid; the patients of esophageal cancer, lung cancer and gastric cancer with abnormal Savda suffer a low concentration of linoleic acid; the patients of esophageal cancer, colorectal cancer, lung cancer and breast cancer with abnormal Savda suffer a high concentration of oleic acid; the patients of breast cancer patients with abnormal Savda suffer a low concentration of stearic acid; the patients of esophageal cancer and gastric cancer with abnormal Savda suffer a low concentration of arachidonic acid; the patients of breast cancer patients with abnormal Savda suffer a high concentration of EPA, but the patients of gastric cancer with abnormal Savda suffer a low concentration of EPA; the patients of esophageal cancer, lung cancer and breast cancer with abnormal Savda suffer a high concentration of arachidic acid; the patients of esophageal cancer and gastric cancer with abnormal Savda suffer a high concentration of DHA. It is concluded that these findings suggest that different tumor patients with abnormal Savda see some common characteristics, and also significant differences.
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Received: 07 March 2014
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2014, Vol. 32 
