Abstract: Gene conversion is defined as a non-reciprocal transfer of information between homologous sequences and has been found in a wide variety of karyotic and eukaryotic organisms. It plays an important role in reversion, concerted evolution, antigenic variation, antibiotic resistance and gap repair. Molecular models, including Holliday model, Meselson-Radding model, DSBR model, and SDSA model, can be used to explain gene conversion. In this paper, these molecular mechanisms, as well as the role of gene conversion in the process of nrDNA concerted evolution we reviewed.
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Received: 21 August 2008
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