Abstract: Gansu Province is subdivided into 9 climate areas in this paper, based on the climatic zoning system proposed by Li Hua, et al, according to the climatic data of general weather stations in Gansu Province during 20 years. In the climatic zoning system, the frost-free period is used as the first index, the dryness index as the second index, and the level of earth burial to keep warm as the third index. Hexi Corridor, the center area of the Baiyin and the countryside of Lanzhou are shown to be the most suitable viticulture zones. Other areas see some unfavorable conditions such as overabundance of moisture in harvest-time, hence, are defined as the ordinary viticulture areas. In other special areas or small areas, high quality wine production also can be expected, a further subdivision is needed. By the comparison of three grapevine variety zoning indexes: Index of Huglin (IH), LTI and the effective active accumulated temperature, considering the actual situation of the viticulture in Gansu Province, the IH in grape growing season is found to be appropriate for variety zoning. And the suitable viticulture varieties are determined for each area through the results.