According to the body fluid theory of Uygur Medicine, 76 cases of asthmatic patients were diagnosed. Among them, there were 30 cases of asthmatic patients with abnormal savda and 46 cases of asthmatic patients with normal savda. The gene polymorphism of IL-13 on loci intron3+1923 and loci +2044 of these patients are tested by using PCR-RFLP, the results are compared with that of the 89 normal individuals in order to explore the relationship between asthmatic Xinjiang Uygur patients with abnormal savda and the gene polymorphism of IL-13. There is significant difference of gene polymorphism of IL-13 on loci intron3+1923 in all three groups(P＜0.01). The distribution rate of genotype TT and TC in asthmatic patients with abnormal savda is significantly higher than that of the asthmatic patients with normal savda and the normal control group(P＜0.01). The distribution rate of genotype TT and TC in asthmatic patients with normal savda is significantly higher than that of the normal control group (P＜0.05). The distribution rate of genotype CC in normal control group is significantly higher than that of the asthmatic patients with abnormal savda(P＜0.01) and higher than that of the asthmatic patients with abnormal savda (P＜0.05). The distribution rate of genotype CC in asthmatic patients with normal savda is significantly higher than that of the asthmatic patients with abnormal savda(P＜0.05). There is significant difference in the distribution rate of allele C and T in all three groups(P＜0.01). The distribution rate of allele T in asthmatic patients with abnormal savda is significantly higher than that of the normal control group(P＜0.01). The distribution rate of allele C in asthmatic patients with abnormal savda is significantly lower than that of the normal control group(P＜0.05). There is insignificant difference in the distribution rate of IL-13 on loci +2044 and the distribution rate of its alleles in all three groups(P＞0.05). In short, Asthma in Xinjiang Uygur Patients with abnormal savda might be related to the gene polymorphism of IL-13 loci intron3+1923, but is not related to the gene polymorphism of IL-13 on loci+ 2044.