During the reservoirs exploration and development, the impedance inversion method based on seismic data could be adopted to predict the reservoir distribution. Especially in the stage of reservoirs development, it is necessary to know the thin layer and thin interbed reservoirs distribution and to take measures in the further development. In order to acquire accurate inversion results, it is important to build a refined initial model. Although the impedance inversion is based on log and geological data, the initial model built on the traditional structure interpretation results is not accurate enough, and is unable to reduce multi-solution problem of seismic inversion. The impedance inversion based on high-resolution sequence stratigraphy framework has been introduced. First the high-resolution sequence stratigraphy classification results could be calibrated in the seismic profile by the synthetic seismogram. Then every sequence interface must be interpreted in the seismic profile. As to the sequence interface that does not have the corresponding seismic wave in seismic profile, it could be traced according to the logging data. The initial model for the log-constrained impedance inversion has been constructed on the basis of the interpretation of high-resolution sequence framework. Finally the reservoirs distribution is able to be required from the inversion results. The method is successfully applied to the Gaotaizi Oil field of Daqing Placanticline. The predictive reservoirs have been confirmed by the later real drilling data. The case study indicates the wide application prospects for the inversion method constrained by high-resolution sequence framework in the prediction of the thin interbed reservoir.