Chain effect of water disaster has been found during the mining process in the underground mining. Taken disaster chain theory and characteristics of the mine into account, the chain-cutting disaster mitigation model and engineering measures are great significant to the underground mine. According to the theory model of disaster chain, the water disaster chain model of a mine in Hunan was built. Elements in water disaster chain model was divided into three collections. The relations among elements in water disaster chain were built as equations. The characteristics of elements changing over times were analyzed. Three approaches of disaster mitigations were proposed for each period of water disaster chain. The 610 level's mine water trouble of the mine in Hunan was taken as an engineer example, the results showed that, the built mine water disaster chain model could effectively describe the characters of mine water disasters. This mine water disaster chain source was mainly formed by the surface water seep and the water storage in goaf. The disaster output was transformed from the chain source through water-conducting induce under the response of mining. The 610 level's water trouble was in the period of disaster burst. Engineering measures were raised to deal with chain-cutting disaster mitigation, control of water disaster and water resources utilization coordinately, such as filling mined-out area, underground drainage and circulation utilization of water resources.