In blasting operation, energy of blasting seismic transferrs differently due to differences in rock structure and construction. In order to control blasting seismic effect effectively, the borehole stress-strain of blasting process is researched by the theoretical study and model test. The relationship of the hole length between duration of vibration and peak strain is investigated respectively. Meanwhile, the seismic effect is compared in different intervals between the shallow hole and deep hole. In addition, amplitude, frequency and duration of vibration are also comprehensive compared. The results show that air interval charge can decrease the blasting seismic effect, and reduce the impact and backlash. Moreover, compared with three loading modes, the vibration reduction is up to 10%-25%. Concretely, the vibration reduction effect is the best through the air interval charge in bottom of hole, and the upper is followed. Blasting seismic effect is maximum in the middle of air-spaced.