The secondary structure, B cell and T cell epitopes for the AgB1 antigen protein of Echinococcus granulosus were predicted and analyzed. According to the gene sequences of AgB1 antigen, the protein secondary structure was analyzed by PredictProtein, and B cell and T cell epitopes of AgB1 were predicted by Internet website Bcepred, Abcpred, IEDB and SYFPEITHI. The results show that many distinct antigenic epitopes of AgB1 were identified by computation, and the high scored B cell epitopes in the regions of 2-9, 15-20, 22-35 and 41-52. The possible T cell epitopes is in the regions of 3-12, 26-33, 34-44 and 52-61. In this study it is determined that there are 4 B cell dominant epitopes and 4 T cell ones in AgB1 antigen by bioinformatics methods,which are significant in the further research of AgB1 antigenic and development of the immune diagnosis method.