Contraflow operation is an important measure in the emergency traffic evacuation. Based on the theory of the cell transmission model (CTM), a contraflow operation model is built with the total travel time as the objective function. With the numerical solution and the microscopic traffic simulation methods combined, the contraflow operation model is solved numerically with MathProg language and Lp_solve solver, the evacuation process is simulated microscopically using the microscopic traffic simulation software VISSIM. The numerical results and the simulation results are compared to make the model closer to the actual situation. The results show that the contraflow operation can significantly improve the road network capacity and the evacuation efficiency.