Effects of thermal aging on the vibration transfer characteristics of expanded polystyrene (EPS) cushion material are studied. The purpose is to provide reference for the cushioning packaging design, and to ensure the protection in current process. The accelerated thermal aging conditions are simulated by the frequency sweep experiments to explore the change regularities of vibration transmissibility with the aging time. The results show that the vibration transmissibility was affected by many factors. Above all, the expanded polystyrene damping ratio rose as increasing the aging time and also the peak values of vibration transmissibility increased. It was found that the peak values of vibration transmissibility increased by 42.66% while load 5.0 kg and 21.96% while 2.5 kg by aging at 240h. Moreover, the transmissibility-frequency curve shift to the upper left with the load rising, and the transmissibility-frequency curve shift to the upper right as increasing the expanded polystyrene density. With due consideration of the analysis above, we may draw a conclusion that it's necessary to fully consider many factors such as the load, material density and thermal aging time, when choosing vibration-proof packaging materials.