The bioinformatic software is used to predict the nucleotide sequence of SH2D7 and the second structure of its encoding protein. It is shown that SH2D7 is located on the human chromosome 15q25.1, containing six exons and five introns. SH2D7 protein is mainly involved in the regulation of the gene expression and the signal transduction. Its molecular weight is 49.8 kD and the isoelectric point is 5.99. SH2D7 is a hydrophilic protein mainly located in the nucleus and there are 35 phosphorylation sites and 22 epitopes bit in the SH2D7 protein sequence.
YANG Hua
,
YANG Fengqin
,
LIAO Guoling
,
LIU Xueying
. Bioinformatic analysis of SH2D7 and its encoded protein[J]. Science & Technology Review, 2015
, 33(2)
: 35
-38
.
DOI: 10.3981/j.issn.1000-7857.2015.02.003
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