This paper analyzes the technical development route of bevacizumab and ranibizumab based on the vascular endothelial growth factor (VEGF) antibody related patent applications of Roche. The layout in China of the VEGF related patents of Roche is also analyzed. Based on the above analyses, the future trends and directions of the technical research and development of VEGF antibody technology are predicted.
ZHANG Chi
,
ZHANG Yinghui
. Analysis of VEGF antibody technology patents of roche[J]. Science & Technology Review, 2016
, 34(11)
: 48
-52
.
DOI: 10.3981/j.issn.1000-7857.2016.11.008
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