Articles

Safety assessment methods and risk evaluation for electronic nicotine delivery system

  • TIAN Yongfeng ,
  • YANG Liu ,
  • DUAN Yuanxing ,
  • ZHAO Wei ,
  • YANG Ji ,
  • GONG Xiaowei ,
  • LI Shoubo ,
  • CHEN Yongkuan
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  • Technology Center of China Tobacco Yunnan Industry Co., Ltd., Kunming 650224, China

Received date: 2015-09-06

  Revised date: 2016-05-13

  Online published: 2017-02-07

Abstract

Electronic nicotine delivery system (ENDS) has the advantage of chemically simple and nicotine contents controllable, and is considered to be the ideal substitute for cigarette. Meanwhile, ENDS is marketed as less harmful alternatives to cigarette because of not burning in the nicotine delivery process and less harmful chemical components in vapor. To deeply study ENDS, DNA damage and mutation caused by tobacco specific nitrosamines (TSNAs) and benzo(a)pyrene in ENDS vapor are reviewed in this paper. Risk evaluation of ENDS in chemical analysis, toxicology, cell exposure, animals experiments and clinical research are also discussed. Finally, the future development of ENDS is prospected.

Cite this article

TIAN Yongfeng , YANG Liu , DUAN Yuanxing , ZHAO Wei , YANG Ji , GONG Xiaowei , LI Shoubo , CHEN Yongkuan . Safety assessment methods and risk evaluation for electronic nicotine delivery system[J]. Science & Technology Review, 2016 , 34(24) : 131 -136 . DOI: 10.3981/j.issn.1000-7857.2016.24.020

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