Spescial Issues

New concept and progress of spontaneous intracerebral hemorrhage

  • HU Rong ,
  • FENG Hua
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  • Chongqing Clinical Research Center for Neurosurgical Disease;Department of Neurosurgery, Southwest Hospital, The Third Military Medical University, Chongqing 400038, China

Received date: 2016-12-01

  Revised date: 2017-02-06

  Online published: 2017-02-28

Abstract

The spontaneous intracerebral hemorrhage (SICH) is associated with high mortality and morbidity rates. The prevention and the treatment of the SICH are the most urgent issues. This review summarizes the definition and the natural history of the SICH, the current understanding of the mechanisms underlying the SICH-induced brain injury and the current state of treatment. The concept of "lenticulostriate-artery neural complex" is proposed to help the study of the mechanisms of the SICH and the key issues in the SICH, to improve the prevention, the diagnosis and the treatment of the SICH and to reduce the mortality and morbidity rates.

Cite this article

HU Rong , FENG Hua . New concept and progress of spontaneous intracerebral hemorrhage[J]. Science & Technology Review, 2017 , 35(4) : 18 -22 . DOI: 10.3981/j.issn.1000-7857.2017.04.001

References

[1] 中华医学会神经外科学分会. 自发性脑出血诊断治疗中国多学科专家共识[J]. 中华急诊医学杂志, 2015, 24(12):1319-1323. Chinese society of Neurosurgery, Chinese College of Emergency Physi-cansl. Expert consensus on diagnosis and treatment of spontaneous cere-bral hemorrhage in China[J]. Chinese Journal of Neurosurgery, 2015, 31(12):1189-1194.
[2] Qureshi A I, Tuhrim S, Broderick J P, et al. Spontaneous intracerebral hemorrhage[J]. New England Journal of Medicine, 2001, 344(19):1450-1460.
[3] van Asch C J J, Luitse M J A, Rinkel G J E, et al. Incidence, case fa-tality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin:A systematic review and metaanalysis[J]. The Lancet Neurology, 2010, 9(2):167-176.
[4] Adeoye O, Broderick J P. Advances in the management of intracerebral hemorrhage[J]. Nature Reviews Neurology, 2010, 6(11):593-601.
[5] Qureshi A I, Suri M F K, Nasar A, et al. Changes in cost and outcome among US patients with stroke hospitalized in 1990 to 1991 and those hospitalized in 2000 to 2001[J]. Stroke, 2007, 38(7):2180-2184.
[6] Feigin V L, Lawes C M M, Bennett D A, et al. Worldwide stroke inci-dence and early case fatality reported in 56 population-based studies:a systematic review[J]. The Lancet Neurology, 2009, 8(4):355-369.
[7] Labovitz D L, Halim A, Boden-Albala B, et al. The incidence of deep and lobar intracerebral hemorrhage in whites, blacks, and Hispanics[J]. Neurology, 2005, 65(4):518-522.
[8] Polychronopoulos P, Gioldasis G, Ellul J, et al. Family history of stroke in stroke types and subtypes[J]. Journal of the Neurological Sciences, 2002, 195(2):117-122.
[9] Liu B, Zhang L, Yang Q. Genetics of intracerebral hemorrhage:Insights from candidate gene approaches[J]. Neurology India, 2012, 60(1):3.
[10] Tzourio C, Arima H, Harrap S, et al. APOE genotype, ethnicity, and the risk of cerebral hemorrhage[J]. Neurology, 2008, 70(16):1322-1328.
[11] Sun L, Li Z, Zhang H, et al. Pentanucleotide TTTTA repeat polymor-phism of apolipoprotein (a) gene and plasma lipoprotein (a) are associ-ated with ischemic and hemorrhagic stroke in Chinese a multicenter case-control study in China[J]. Stroke, 2003, 34(7):1617-1622.
[12] Flaherty M L. Anticoagulant-associated intracerebral hemorrhage[J]. Seminars in Neurology, 2010, 30(5):565-572.
[13] Xi G, Keep R F, Hoff J T. Mechanisms of brain injury after intracere-bral haemorrhage[J]. The Lancet Neurology, 2006, 5(1):53-63.
[14] Matsukawa H, Shinoda M, Fujii M, et al. Factors associated with lobar vs. non-lobar intracerebral hemorrhage[J]. Acta Neurologica Scandi-navica, 2012, 126(2):116-121.
[15] Takebayashi S, Kaneko M. Electron microscopic studies of ruptured ar-teries in hypertensive intracerebral hemorrhage[J]. Stroke, 1983, 14(1):28-36.
[16] Tan J, Wang B, Zhu L. DNA binding, cytotoxicity, apoptotic inducing activity, and molecular modeling study of quercetin zinc (II) complex[J]. Bioorganic & medicinal chemistry, 2009, 17(2):614-620.
[17] Rosand J, Hylek E M, O'Donnell H C, et al. Warfarin-associated hemorrhage and cerebral amyloid angiopathy A genetic and pathologic study[J]. Neurology, 2000, 55(7):947-951.
[18] Keep R F, Hua Y, Xi G. Intracerebral haemorrhage:mechanisms of in-jury and therapeutic targets[J]. The Lancet Neurology, 2012, 11(8):720-731.
[19] Rodriguez-Luna D, Coscojuela P, Rubiera M, et al. Ultraearly hemato-ma growth in active intracerebral hemorrhage[J]. Neurology, 2016, 87(4):357-364.
[20] Chamorro Á, Meisel A, Planas A M, et al. The immunology of acute stroke[J]. Nature Reviews Neurology, 2012, 8(7):401-410.
[21] Ransohoff R M, Brown M A. Innate immunity in the central nervous system[J]. The Journal of Clinical Investigation, 2012, 122(4):1164-1171.
[22] Hemphill J C, Greenberg S M, Anderson C S, et al. Guidelines for the management of spontaneous intracerebral hemorrhage a guideline for healthcare professionals from the American Heart Association/Ameri-can Stroke Association[J]. Stroke, 2015, 46(7):2032-2060.
[23] Anderson C S, Huang Y, Wang J G, et al. Intensive blood pressure re-duction in acute cerebral haemorrhage trial (INTERACT):A ran-domised pilot trial[J]. The Lancet Neurology, 2008, 7(5):391-399.
[24] Anderson C S, Heeley E, Huang Y, et al. Rapid blood-pressure lower-ing in patients with acute intracerebral hemorrhage[J]. New England Journal of Medicine, 2013, 368(25):2355-2365.
[25] Ziai W C, Tuhrim S, Lane K, et al. A multicenter, randomized, dou-ble-blinded, placebo-controlled phase III study of Clot Lysis Evalua-tion of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III)[J]. International Journal of Stroke, 2014, 9(4):536-542.
[26] Mendelow A D, Gregson B A, Fernandes H M, et al. Early surgery ver-sus initial conservative treatment in patients with spontaneous supra-tentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH):A randomised trial[J]. The Lan-cet, 2005, 365(9457):387-397.
[27] Mendelow A D, Gregson B A, Rowan E N, et al. Early surgery versus initial conservative treatment in patients with spontaneous supratentori-al lobar intracerebral haematomas (STICH II):A randomised trial[J]. The Lancet, 2013, 382(9890):397-408.
[28] 卢琦萍. 弘扬不朽志强精神, 锻造时代外科人才[J]. 中华消化外科杂志, 2016, 4(15):310-315. Lu Qiping. Carring forward the immortal Zhiqiang spirit and cultivat-ing the surgery talents of the ear[J]. Chinese Journal of Digestive Sur-gery, 2016, 4(15):310-315.
[29] Kumar P, Yadav A K, Misra S, et al. Prediction of upper extremity mo-tor recovery after subacute intracerebral hemorrhage through diffusion tensor imaging:a systematic review and meta-analysis[J]. Neuroradiol-ogy, 2016, 58(10):1043-1050.
[30] Chen S, Chen Y, Xu L, et al. Venous system in acute brain injury:Mechanisms of pathophysiological change and function[J]. Experimen-tal Neurology, 2015, 272:4-10.
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