Science & Technology Review >

2017 , Vol. 35 >Issue 24: 32 - 39

DOI: https://doi.org/10.3981/j.issn.1000-7857.2017.24.003

Special Issues

Advancement of science and technology and laboratory animal welfare

  • LI Changlong ,
  • SHANG Shujiang ,
  • ZHU Desheng
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  • 1. School of Basic Medical Science, Capital Medical University, Beijing 100069, China;
    2. Laboratory Animal Center, Peking University, Beijing 100871, China

Received date: 2017-07-02

  Revised date: 2017-11-30

  Online published: 2017-12-29

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Abstract

The laboratory animal is an important tool in the life science and the biomedical industry. The laboratory animal welfare not only ensures animals'health and happiness, but is also important for generating accurate, reliable, and repeatable results in the laboratory. With the development of society, more and more researchers become aware of the significance of the laboratory animal welfare. Ensuring the laboratory animal welfare facilitates the progress of science and technology. At the same time, the progress of science and technology also promotes the laboratory animal welfare. This paper reviews the history of the development of the concept and the requirements of the laboratory animal welfare. The mutual beneficial role between the progress of science and technology and the development of the laboratory animal welfare is specially addressed. The deficiency in the laboratory animal welfare in China is pointed out, and it is hoped that the laboratory animals can better serve the human health and the social development.

Key words： laboratory animal; laboratory animal welfare; 3R principle

Cite this article

LI Changlong , SHANG Shujiang , ZHU Desheng . Advancement of science and technology and laboratory animal welfare[J]. Science & Technology Review, 2017 , 35(24) : 32 -39 . DOI: 10.3981/j.issn.1000-7857.2017.24.003

References

[1] 朱德生, 曾林, 贺争鸣, 等. 我国实验动物福利发展战略与十二五生命科技发展需求及对策的探讨[J]. 中国比较医学杂志, 2011, 21(10):57-60. Zhu Desheng, Zeng Lin, He Zhangping, et al. Development strategy for laboratory animal welfare in China:A discussion on how to meet and re-spond to the needs and challenges of the 12th five-year plan on devel-oping life sciences and technology in China[J]. Chinese Journal of Com-parative Medicine, 2011, 21(10):57-60.
[2] 中国科学技术协会. 实验动物学学科发展报告[M]. 北京:中国科学技术出版社, 2009. China Association for Science and Technology. Report on advances in laboratory animal Science[M]. Beijing:China Science and Technology Press, 2009.
[3] Hume C W. The strategy and tactics of experimentation[J]. Lancet, 1957, 270(7004):1049-1052.
[4] Hughes B O. Behavior as an index of welfare[C]. Proceeding V Europe-an Poultry Conference. Malta Branch:World Poultry Science Associa-tion, 5-11 September, 1976.
[5] Carpenter E Animals and ethics[M]. London:Watkins Publishing, 1980.
[6] Carenzi C, Verga M, Scipioni R, et al. Animal welfare:review of the sci-entific concept and definition.[J]. Italian Journal of Animal Science, 2010, 8(S1):21-30.
[7] 《实验动物福利伦理审查指南》 国家标准征求意见稿[EB/OL].[2017-11-20]. http://www.lascn.net/UploadFiles/2016/4/201604111021491862.pdf. Laboratory Animals-Guideline of welfare and ethics[EB/OL].[2017-11-20] http://www.lascn.net/UploadFiles/2016/4/201604111021491862.pdf.
[8] Koknaroglu H, Akunal T. Animal welfare:An animal science approach[J]. Meat Science, 2013, 95(4):821-827.
[9] 赵怡红. 实验动物研究所通过AAALAC认证现场评估[J]. 中国比较医学杂志, 2007, 17(2):71. Zhao Yihong. Institue of laboratory animal sciences through AAALAC certification field assessment Chinese Journal of Comparative Medicine, 2007, 17(2):71.
[10] 崔树良. 实验动物的质量控制[J]. 实验动物科学, 1992(1):41-44. Cui Shuliang. Laboratory animal quality control[J]. Laboratory Animal Science, 1992(1):41-44.
[11] Cathy L, Kenneth L, Dave T, et al. Comfortable quarters for laboratory animals[M]. Washington, DC:Animal Welfare Institute, 1979.
[12] Russell W M S, Burch R L. The principles of humane experimental technique[M]. London:Universities Federation for Animal Welfare, 1959.
[13] OECD considers animal welfare in the development of test guidelines[EB/OL].[2017-11-20]. http://www.oecd.org/chemicalsafety/testing/ani-mal-welfare.htm.
[14] 战大伟, 江其辉, 仇志华, 等. 独立通风笼(IVC)在实验动物学中的应用[J]. 中国比较医学杂志, 2006, 16(10):631-634. Zhan Dawei, Jiang Qihui, Qiu Zhihua, et al. Application of individual-ly ventilated cage system in laboratory animal sciences[J]. Chinese Journal of Comparative Medicine, 2006, 16(10):631-634.
[15] 柯贤福, 陈文文, 卢领群, 等. 四种独立通风笼具(IVC)的检测[J]. 中国比较医学杂志, 2009, 19(9):78-82. Ke Xianfu, Chen Wenwen, Lu Lingqun, et al. Environment parameters of four types of individually ventilated cages (IVC)[J]. Chinese Journal of Comparative Medicine, 2009, 19(9):78-82.
[16] 郭瀚元, 定明. 国内外实验动物玩具的发展现状及展望[J]. 实验动物科学, 2016, 33(6):64-66. Guo Hanyuan, Ding Ming. Development and prospect of laboratory ani-mals toys in China and abroad[J]. Laboratory Animal Science, 2016, 33(6):64-66.
[17] Du X Y, Li W, Sa X Y, et al. Selection of an effective microsatellite marker system for genetic control and analysis of gerbil populations in China[J]. Genetics & Molecular Research, 2015, 14(3):11030-11042.
[18] 王存龙, 李长龙, 邢进, 等. 活体长爪沙鼠幽门螺杆菌检测方法的建立[J]. 中国比较医学杂志, 2017, 27(3):75-80. Wang Cunlong, Li Changlong, Xing Jin, et al. Establishment of a de-tection method for Helicobacter pylori in living Mongolian gerbil[J]. Chinese Journal of Comparative Medicine, 2017, 27(3):75-80.
[19] 马元元, 孔申申, 陶迎红, 等. 实验动物设施内哨兵鼠对病原菌监控的研究[J]. 实验动物科学, 2012, 29(4):25-28. Ma Yuanyuan, Kong Shenshen, Tao Yinghong, et al. The bacteria and mycoplasma monitoring in the laboratory animal facility by using senti-nel mice[J]. Laboratory Animal Science, 2012, 29(4):25-28.
[20] 全国认证认可标准化技术委员会实验室认可分技术委员会. GB/T 27416-2014《实验动物机构质量和能力的通用要求》理解与实施[M]. 北京:中国标准出版社, 2015.
[21] 赵远, 谢明学, 王祥, 等. 疫苗研发及生产过程中实验动物福利的探讨[J]. 中国疫苗和免疫, 2016(4):465-468. Zhao Yuan, Xie Xueming, Wang Xiang, et al. Laboratory animal wel-fare in vaccine research and production[J]. Chinese Journal of Vac-cines and Immunization, 2016(4):465-468.
[22] 范灿鹏, 王奇, 刘昕宇, 等. 四溴联苯醚对剑尾鱼毒性及其抗氧化系统的影响[J]. 环境科学学报, 2011, 31(3):642-648. Fan Canpeng, Wang Qi, Liu Xinyu, et al. Toxicity and effect of tetra-bromodiphenyl ether upon the antioxidant defense system of swordtail fish (Xiphophorus helleri)[J]. Acta Scientiae Circumstantiae, 2011, 31(3):642-648.
[23] Rosenbaum Sara, 郭磊. 基础药代动力学和药效学——整合式教科书与计算机模拟[J]. 基础医学与临床, 2012(8):898. Rosenbaum Sara, Guo Lei. Basic pharmacokinetics and pharmacody-namics[J]. Basic & Clinical Medicine 2012(8):898.
[24] 恽时锋, 田小芸, 郭联庆, 等. 维护实验动物福利促进生命科学发展[J]. 医学研究生学报, 2009, 22(8):858-861. Yun Shifeng, Tian Xiaoyun, Guo Lianqing, et al. Stressing the welfare of laboratory animals to advance life science[J]. Journal of Medical Postgraduates, 2009, 22(8):858-861.
[25] 赵金晶, 李春华, 冯旭辉, 等. 清醒高血压大鼠心率变异分析的动物模型建立[J]. 中国应用生理学杂志, 2006, 22(1):62-63. Zhao Jinjing, Li Chunhua, Feng Xuhui, et al. The establishment of ani-mal models for analyzing heart rate variability in conscious rats with hypertension[J]. Chinese Journal of Applied Physiology, 2006, 22(1):62-63.
[26] 师长宏. 影像技术在动物实验中的应用[J]. 实验动物科学, 2016, 33(2):66-70. Shi Changhong. The application of image technology in animal experi-ment[J]. Laboratory Animal Science, 2016, 33(2):66-70.
[27] 李岗. 光学分子影像技术在肝癌动物模型构建及诊疗中的应用研究[D]. 广州:南方医科大学, 2015. Li Gang. Application of optical molecular imaging technology in the research of animal model establishment and diagnosis of liver Cancer[D]. Guangzhou:Southern Medical University, 2015.
[28] 陈华. 微创外科与动物实验伦理[J]. 实验动物科学, 2012, 29(2):44-47. Chen Hua. Minimaly invasive surgery and the ethics of animal experi-mentation[J]. Laboratory Animal Science, 2012, 29(2):44-47.
[29] Jane G. Learning from the chimpanzees:A message humans can under-stand[J]. Science, 1998, 282(5397):2184-2185.
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