In Daniudi gas field there are many gas bearing segments, and the sand bodies are highly heterogeneous with great lateral variations, so the differences of the wave impedance are indistinct. Based on the stratigraphic framework, the seismic waveform differences of the reservoir are analyzed according to the production information of wells. There are some differences in the center, probability, and characteristic value of centroid, mean, variance and varying variance for the seismic waves from nearby wells between different production layers, but the sensibility is not enough. In order to obtain seismic waveform parameters of gas bearing formation with higher sensitivity, the seismic waveform sensitive formation is analyzed and reconstructed, and seven waveform parameters are obtained. By analysis and reconstruction of the sensitive information, the corresponding relationship among reservoirs of different productivity and seismic waves is established, and the data of waveform differences are obtained by inversion for the target stratum with this relationship. Combined with geological information, sedimentary facies etc. the waveform difference data are interpreted, and the high gas area layer prediction diagram of the target stratum is obtained. With the data of production wells and new production wells in this area, the prediction results are analyzed, and the total prediction agreement rate reaches 86%.