Through the observation and the reflection on the situation related to the prevention and the control of the new crown virus infection in Wuhan, this paper suggests that some important problems should be considered in the decision-making of the epidemic disease prevention and control, and the philosophy behind the prevention and the control of the infectious diseases in five aspects, including the infectivity, the epidemiology, the cost-effective, the compassion and the rule of law. It is proposed to establish two sets of standards for the early prevention and control and in the stage of the epidemic out of control, accordingly, in order to assist the scientific decision-making and the rational measures to effectively reduce the damage to life and property and economic and social losses caused by the epidemic situation.