To promote the effective connection between rural revitalization and poverty alleviation is an important way to consolidate the achievements of poverty alleviation, further release the endogenous impetus of rural development and realize agricultural and rural modernization. This article sorts out the coordination and convergence between poverty alleviation and rural revitalization five development and evolution processes of Liangshan Yi Autonomous Prefecture from poverty alleviation to rural revitalization, namely poverty assistance with system reform as the core, poverty assistance with economic development as the core, poverty assistance with poor areas as the core, and poverty assistance with precision as the core. Then an in-depth analysis of the internal logical consistency and continuity of poverty alleviation and rural vitalization is presented, followed by a cohesive mechanism between poverty alleviation and rural vitalization constructed from both macro and micro levels. Based on the actual situation of Liangshan Yi Autonomous Prefecture and the regional classification standard of existing literature research, the prefecture is divided into four regions:river valley settlement area, hilly settlement area, settlement area, and high-mountain settlement area, and a differentiated promotion path of rural revitalization is proposed according to the regional characteristics. This paper also discusses the construction of supporting mechanisms from four aspects, i.e., stimulating internal driving force of rural development, consolidating institutional guarantee of rural vitalization, promoting rural vitalization by zoning and classification, and improving the link between rural vitalization and other development strategies.