In the "Opinions on the development of technology market" issued by the ministry of science and technology in 2018, the construction of a hub technology trading market was clearly identified as the overall direction of China's technology market development. As an important participant in the technology trading activities, China Association for Science and Technology plays an important role in building a pivotal technology market. Based on the SWOT method, this paper analyzes the advantages, the disadvantages, the opportunities and the challenges of China Association for Science and Technology in participating in the activities of the hub technology trading market, and further five aspects put forward concrete Suggestions. First, to complete the top of the hub type technology trading market design and supporting infrastructure, accelerate the technical market rules and relevant legal policy research. Second, to build a platform for technology transformation, participate in the design of supporting policies, carry out research on technology pricing, introduce professional financial capital, and promote the coordinated development of various entities in the technology trading market. Third, to stimulate the resource advantages of the high-end think tank of the China Association for Science and Technology, and further improve the quality of public science and technology services such as policy consultation and forecast of science and technology development. Fourth, to cultivate professional international technology transfer personnel team and establish relevant personnel assessment system. Fifth, expand the international influence of the association by grasping the opportunity of the Belt and Road Initiative.