Precision medicine has greatly changed the concept of disease treatment and the mode of diagnosis and treatment, bringing unprecedented health benefits to human beings. Due to the complex interaction between individual and group in precision medicine, there arises a series of ethical issues, such as the paradoxes of privacy between individual patients and groups of patients, individual patients’lack of trust towards groups of medical personnel, coexistence of cooperation and competition between individual medical personnel and groups of medical personnel, and individual doctors bearing more and more ethical responsibility on groups of patients. This article argues that only when we agree with the value concept and practical needs of precision medicine, lay a basis of ethical consideration, and review the individual and group relationship in precision medicine, can we construct a“a community of shared future for patients”that strikes a balance between privacy protection and information sharing, a harmonious and friendly“doctor-patient community” , a“medical personnel community”with cohesive force, and improve the professional ethics of medical personnel to promote the realization of China’ s precision medicine strategy that everyone can participate in and share.
TAO Yingshi
,
CHEN Qiao
. Ethical analysis of individual and group relationship in precision medicine[J]. Science & Technology Review, 2022
, 40(18)
: 63
-68
.
DOI: 10.3981/j. issn. 1000-7857.2022.18.008
[1] 管泽宇, 张大庆, 李维. 从个体化医学、 个性化医学到精准医学的概念演变史[J]. 中国科技史杂志, 2017, 38(4): 398-410.
[2] National Research Council. Toward precision medicine: Building a knowledge network for biomedical[R]. Washington: NRC, 2011.
[3] Barack O. President Obama's state of the union addressremarks as prepared for delivery[EB/OL]. (2013-02-12) [2021-05-16]. https://obamawhitehouse.archives.gov/thepress-office/2013/02/12/president-barack-obamas-stateunion-address-prepared-delivery.
[4] Cyranoski D. China embraces precision medicine on a massive scale[J]. Nature, 2016, 529(7584): 9-10.
[5] 中华人民共和国国民经济和社会发展第十三个五年规划纲要[EB/OL]. (2016-03-17)[2021-03-19]. http://www.gov.cn/xinwen/2016-03/17/content_5054992.htm.
[6] 陶应时, 王国豫. 精准医学伦理: 当代生命伦理研究的新领域[J]. 自然辩证法通讯, 2019, 41(7): 93-99.
[7] 陶应时, 王国豫. 精准医学伦理构建: 理念、 原则与路径[J]. 科学学研究, 2020, 38(6): 961-967.
[8] 田海平. 大数据时代的健康革命与伦理挑战[J]. 深圳大学学报, 2017, 34(2): 5-16.
[9] 谈琳. 白银连环杀人案告破凸显科技的力量[N]. 科技日报, 2016-8-30(08).
[10] Barbara P. Genetic Data and the Law: A critical perspective on privacy protection[J]. Medical Law Review, 2012(2): 291-295.
[11] Minikel E V, Vallabh S M, Lek M, et a1. Quantifying prion disease penetranee using large population control eohorts[J]. Science Translational Medicine, 2016, 8(322): 322ra9.
[12] Chouchane L, Mamtani R, Dallol A, et al. Personalized medicine: A patient-centered paradigm[J]. Journal of Translational Medicine, 2011, 9(1): 1-3.
[13] Yarden Y, Pines G. The ERBB network: At last, cancer therapy meets systems biology[J]. Nature Reviews Cancer, 2012, 12(8): 553-563.
[14] 曹宪姣, 朱见, 贺青卿. 对医学高新科技伦理争议的思考[J]. 医学与哲学, 2019, 40(19): 44-48.
[15] Helsinki W. World medical association declaration of helsinki: Ethical principles for medical research involving human subjects[J]. Hiv Clinical Trials, 2000, 2(4): 92-95.
[16] Largent E A, Joffe S, Miller F G. Can research and care be ethically integrated[J]. Hastings Center Report, 2011, 41(4): 37-46.
[17] 李蕴, 李文斌. 浅析精准医学与健康医疗大数据[J]. 继续医学教育, 2021, 35(6): 57-59.
[18] Gold E R, Carbone J. Myriad Genetics: In the eye of the policy storm[J]. Genetics in Medicine, 2010, 12(Suppl. 4): 471-472.
[19] 伊浩然. 人类基因的可专利性及利益平衡问题研究[D]. 唐山: 华北理工大学, 2019.
[20] Dion-Labrie M, Fortin M C, He?bert M J, et al. The use of personalized medicine for patient selection for renal transplantation: Physicians'views on the clinical and ethical implications[J]. BMC Medical Ethics, 2010, 11: 5- 14.
[21] Lunshof J E. Personalized medicine: New perspectivesnew ethics?[J]. Personalized Medicine, 2006, 3(2): 187- 194.
[22] 邱仁宗, 翟晓梅. 精准医学时代或面临的五大伦理挑战[N]. 健康报, 2016-12-23(05).
