Science and Technology Humanities

Karl Barry Sharpless: A chemist who was awarded his second Nobel Prize

  • CHEN Biao ,
  • WANG Yan ,
  • ZHANG Yan ,
  • LI Tingting ,
  • ZHU Yuewei ,
  • LI Gong ,
  • WU Youjin
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  • 1. Department of History of Science and Scientific Archaeology, University of Science and Technology of China, Hefei 230026, China
    2. No. 26 Senior High School of Nanning, Nanning 530022, China

Received date: 2023-01-18

  Revised date: 2023-02-10

  Online published: 2023-04-27

Abstract

The Nobel Prize in Chemistry 2022 was jointly awarded to Carolyn Ruth Bertozzi, Morten Meldal and Karl Barry Sharpless for the development of click chemistry and bioorthogonal chemistry. Sharpless has won the Nobel Prize in Chemistry for the second time since 2001. This paper reviews his scientific research and achievements in the field of click chemistry, analyzes the characteristics of click chemistry, that is, simplicity and efficiency. Meanwhile, the paper points out that his research direction changing from chiral catalytic oxidation reaction to click chemistry reflects the scientific spirit of selfbreakthrough and never-ending and the interdisciplinarity of his study also reveals the way to cultivate innovative scientists.

Cite this article

CHEN Biao , WANG Yan , ZHANG Yan , LI Tingting , ZHU Yuewei , LI Gong , WU Youjin . Karl Barry Sharpless: A chemist who was awarded his second Nobel Prize[J]. Science & Technology Review, 2023 , 41(3) : 89 -94 . DOI: 10.3981/j.issn.1000-7857.2023.03.010

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