Exclusive: Science and Technology Review in 2023

Research highlights of bioscience in 2023

  • ZHANG Wenyang ,
  • YANG Yuge ,
  • ZHU Hengle ,
  • ZHU Fang ,
  • WANG Chengcheng ,
  • HU Ronggui
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  • 1. Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Shanghai 200032, China;
    2. Medical School, Guizhou University, Guiyang 550025, China

Received date: 2023-12-30

  Revised date: 2024-01-05

  Online published: 2024-04-09

Abstract

In 2023, breakthrough advancements were made in various fields of life sciences. This article mainly reviews some of those developments that have changed and will likely continue to change our technological, perspective, and investigative approaches to life sciences: The artificial intelligence as an increasingly powerful and important tool for applications in life sciences and medicine; The emergence and unprecedentedly widespread use of GLP-1 agonists; the further optimization and application of new technologies in areas such as phase separation, in vitro embryo models, neuroscience, and developmental biology; and the advent and initial clinical application of new clinical treatments like antibody therapy against beta-amyloid,stem cell and immunotherapy, mRNA vaccines, and CRISPR gene-editing therapies. These research advancements are not only further expanding our understanding of the mysteries of life itself but also bringing hope to patients suffering from a series of significant human diseases such as Alzheimer's, cancer, viral infections, and more.

Cite this article

ZHANG Wenyang , YANG Yuge , ZHU Hengle , ZHU Fang , WANG Chengcheng , HU Ronggui . Research highlights of bioscience in 2023[J]. Science & Technology Review, 2024 , 42(1) : 150 -173 . DOI: 10.3981/j.issn.1000-7857.2024.01.010

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