Based on the actual projects, tests of concrete cubic-compressive strength, tests of elastic modulus, and tests of durability involving the concrete which cement is replaced with the same amount of nano-SiO₂ making concrete blocks in the age periods of 7, 28, and 56 days are respectively conducted. The data is analyzed, and the numerical relationship between incorporation of nano-SiO₂ and concrete strength elevation is studied by using linear regression method. The calculation expression for the cubic-compressive strength of concrete with nano-SiO₂ content and concrete periods of 7, 28, and 56 days is established. The test data of elastic modulus is statistically analyzed, and the ways for improving and increasing of elastic modulus in different concrete ages with different contents of nano-SiO₂, the effects of nano-SiO₂ on the change of concrete microstructure and on the increase of anti-penetration grade and chloride-penetration resistance are explored. The best mixing amount of nano-SiO₂ is obtained in order to guide the production of concrete contained nano-SiO₂.