Employing wet-chemical method, the Al2O3 powder was packaged with nano-material, through the low-temperature solid-state sintering method, large-size and high-performance asymmetric ceramic membranes were obtained, and the properties of 0.2μm asymmetric ceramic membrane were studied as well. It is demonstrated that the pore size distribution of the ceramic membrane is concentrated in the range of 0.1—0.2μm and its surface is in a perfect condition without any defects. The water flux of the ceramic membranes is stably above 3000L·m^-2·h^-1. The rejection of gibberellin is excellent. Burst pressure test shows that the membrane would break under the pressure of 7.5MPa. Moreover, the membrane would break under the pressure of 3.5MPa after soaking with the 20%wt sulfuric acid and 5%wt sodium hydroxide at 100℃ for 36h. All of above results indicate that the prepared asymmetric ceramic membrane in the work not only exhibits good performance under the working environment of less than 1.0MPa and pH value of 1—14, but also meets the requirements of most separation process under the extreme environment.