Taking Ca-bentonite of Zhanyi County, Qujing City, Yunnan Province as the raw material, after drying, the moisture content is less than 5%, and broken into particles of 3—5mm. Acidification reagents are consisted of the volume fraction of 15% sulfuric acid, hydrochloric acid and oxalic acid saturated solution. Add acidification reagents to the wheel grinding machine for rolling. After a certain period of time, add Ca(OH)2 and adjust the material to 5 or 6 pH values, meanwhile add reductant sodium dithionite (Na₂S₂O₄). After 5 minutes, stop working and discharging, drying the material at 110℃, preparing of high efficient active floridin after crushing. The research results indicate that the main factors influencing the activity and decolorization ratio of floridin include mixed acid concentration, solid-to-acid ratio, rolling time, moisture content and reducing agent dosage. When the mixed acid volume fraction is 15%, solid-to-acid ratio is 4:1, moisture content is 22%, rolling time is 40min and reducing agent dosage is 0.8%, it is possible to prepare the high-efficient active floridin with active degree being 204, decolorization ratio being 96%, the relative brightness being 82.