In order to observe the antioxidant effect of different proportions of flos puerariae lobatae and hoveniae semoveniae semen extracted by alcohol and water, at the same time to determine whether different methods of extraction will have different effects and which method is better, alcoholism rat models were induced by administrating wine and Wistar rats were randomly divided into the normal group, the model group, the positive group, the flos puerariae group, the group of seeds of hovenia dulcis Thunb, and the groups of different ratios of compatibility. All rats were killed and their livers and blood were taken to examine the serum alanine aminotransferase (ALT), the serum aspartate aminotransferase (AST) and the Alkaline Phosphatase Kit (ALP). It is shown that the model test is successful and each treatment group sees a certain improvement of the liver function, and the water extraction on the whole is better than the alcohol extract as far as the effect is concerned. It is suggested that the heavy drinking can cause liver damage, the Gehua with the seeds of hovenia different proportion on the alcoholic liver injury in the rat liver has a protective effect, and the traditional water extraction of the drug application used in the experiment is better than the alcohol one.