In order to evaluate the adaptation of reconstructed water-resisting wall for the prevention and control of water disasters during the mining transferring period from open-air to underground, by taking water control project of Xinqiao Mining Corporation in Anhui Province as example, a numerical analysis was conducted. Considering the large supply of open pit water, surface water seepage, and northern lateral flow in the condition of strong rainfall, a stratigraphic model is established by using 3DMINE, and through syncopating profile into the Map module of software GMS8.0, a complex concept model with many layers is created and then based on the Modflow module of GMS8.0, a seepage numerical model of ground water region during open pit mining transferring to underground mining under the condition of many plagues source is established. Results show that GMS8.0 software is able to finely and real-time simulate and rebuilt a water-resisting dynamic process for the prevention and control of water under complex hydrogeological conditions. For the part of reconstructed water-resisting inside and outside wall that the elevation is above -180m, the hydraulic gradient change is large. And water block effect is obvious and has strong adaptability.