The terms "Web 3.0" and "Metaverse" now both refer to the third generation of the Internet. A theoretical framework for Web 3.0/Metaverse is constructed, which consists of three parts. The first part is the Web 3.0/Metaverse architecture, including the structure of the Internet at the Web 3.0/Metaverse system level and the structure of computers as the Internet end systems at the Web 3.0/Metaverse component level. The second part is the Web 3.0/Metaverse technology system, including nine Web 3.0/Metaverse technologies. The third part is the Web 3.0/Metaverse application world, which structurely integrates the virtual and real worlds into one and covers five fields, namely economy, politics, military, society, and culture, in either function or scene. A Web 3.0/Metaverse application system is a field or subsystem, or sub-subsystem, etc. of the Web 3.0/Metaverse application world. A kind of Web 3.0/Metaverse application, digital twinning, is analyzed. The first-principle of blockchain is proposed: in the Web 3.0/Metaverse application world, the core function of blockchain is to make contrust (common trust).

Triboelectric nanogenerator (TENG) has become an emerging platform technology for achieving mechano-electrical energy conversion, with huge application potentials in a variety of fields. For the past decade, through extensive efforts, significant progress on the research of TENG has been made worldwide, including both fundamental scientific research and application technology of TENGs. Therefore, this article aims to review the representative achievements of TENGs in fundamental findings and technological innovations and look forward to the faster development of TENGs.

Chiplet technology is a new generation of integrated circuit technology that has emerged in recent years. It has been widely recognized by the industry due to its excellent characteristics such as improving yield, breaking the limit of reticle size, flexibility in chip architecture, and standardization of IP supply chain. To further promote the development of chiplet technology in China, this article summarizes the application scenarios of chiplet technology, analyzes various core component technologies, elaborates on various technical challenges that may arise in the development of chiplet technology, reviews the development of China’s chiplet standards, and finally, puts forward some suggestions for the development of chiplet technology in China.

This paper summarizes five characteristics of China's standardization "going out" in terms of innovation ability demand, domestic and foreign policies, development stage transformation, existing problems and breakthrough points. Around the government, scientific research institutions and enterprises respectively from the "strategy and policy formulation, theory and decision support, standard development and participation" and other aspects of China's standard "going out" optimization path.

In January 2023, the latest report of American Cancer Statistics in 2023 was published in CA: A Cancer Journal for Clinicians. This report elaborated on the cancer prevalence in America under the COVID-19 pandemic for the first time, described the secular trends in the burden of major cancers, and projected the cancer cases and deaths in 2023. We analyzed the pattern of cancers distribution by geographic area, time, and characteristics of the populations in China and America according to systematical interpretation of the report combined with the cancer statistics in China. We also summarized the current challenges in the development of cancer prevention and control system in China, and provided insights for its construction depending on assessing advancements and underlying reasons of that in America.

Qian Xuesen was the founder of China's aerospace industry and an internationally renowned scientist and he also was the outstanding representative of China's scientist spirit. This article summarizes the connotation of Qian Xuesen's scientist spirit from six aspects: patriotism, innovation, seeking truth, dedication, collaboration, and education. Qian Xuesen's scientist spirit has injected a permanent scientific spirit and innovative momentum into China's national defense technology innovation and high-level technological self-reliance and self-improvement.

The pioneering breakthroughs in materials continue to trigger explosive growth in high-tech and emerging industries.Advanced materials have become a key area of focus and development for countries to seize the technological commanding elevation, and are a fundamental and leading industry for economic and social development. The development of advanced materials determines the level of development in high-tech, emerging industries, high-end manufacturing and major engineering.This paper systematically analyzes the current development status of advanced materials field in China, summarizes major technology plans and development system capabilities, and proposes strategic directions and policy measures for the future development in advanced materials field of China.

As a broadly interdisciplinary field, Human-Computer Interaction (HCI) has become a significant driving force in advancing the development of the information age and bringing computing technologies to the public for everyone to use. This article reviews key topics in the field of HCI until now, and it also explores the evolutionary path of ideas behind the technologies, presenting a more macroscopic philosophical understanding of human-computer relationship and future innovation in the human context. The article is divided into four parts: (1) It briefly describes the position and contributions of HCI; (2) It analyzes the evolution of current technological phenomena from the history of HCI; (3) By understanding the antibiosis issues between humans and computers, the article also applies“Human-Engaged Computing”theory to a discussion about the ideal relationship between humans and technology; (4) Based on the above, we also present suggestions for future development from five aspects: academic thought, research and education, societal impacts, information dissemination, and technology design.

With the advances in technologies of artificial intelligence and 5G as well as the emerging concepts of blockchain and decentralized management, the next revolution of Internet, Web 3.0, has appeared. It will change the development of Internet and various professions and has thus attracted much attention from both academia and industry. This article analyzes the opportunities and challenges of Web 3.0. First, the differences among Web 1.0, Web 2.0, and Web 3.0 are elaborated, and the technical architecture of Web 3.0 is also studied. Second, through studying existing relevant literature, the current development status and the opportunities of Web 3.0 are summarized from both economic and technological aspects. Third, the challenges faced by Web 3.0 in research and regulation are pointed out. Finally, an outlook on the future development of Web 3.0 is given.

科学的飞速发展和文化的缓慢变化发生了矛盾。百年来，中国对传统文化的主流观点曾经出现多次反复，至今缺乏系统的反思，成为当前学术界发挥科学创新潜力的一大障碍。本文从历史回顾和中外比较入手，提出当现代科学在欧洲产生时，中国曾坐失参与的良机；当试图引入西方科技时，又因为方向错误遭受失败，结果使得科学成为西方的特色和东方的弱点。东西方差异的根源在于大陆文明和海洋文明的不同属性，可以上溯到2000多年前古希腊和春秋列国的2大源头。当今世界上这2大文明的经济基础正在消失，新时代的科技发展必将产生新型的全球文明。呼吁从历史反思入手，重新认识中国传统文化，争当国际学术界铸造全球新文明的排头兵。

党的二十大报告指出：“尊重自然、顺应自然、保护自然，是全面建设社会主义现代化国家的内在要求。”随着国家“双碳”战略的稳步推进，绿色转型、绿色消费、低碳产业无疑是未来40年时代发展的主旋律。

The rapid development of high-speed aircraft, microelectronic devices and other fields puts forward higher requirements for the thermal conductivity of thermal management materials. Graphene with excellent thermal conductivity and electrical conductivity is an ideal new generation of thermal management materials. The research status and development prospect of graphene as a high thermal conductivity material are introduced. Firstly, the preparation methods of graphene materials are summarized, including mechanical peeling, epitaxial growth, chemical vapor deposition and redox. Thermal conductivity mechanisms of different types of graphene materials are discussed. Graphene materials carry out heat conduction through phonons and electrons with phonon heat conduction being the mainstay. The thermal resistance network model and thermal conduction permeability model are discussed. The research progress and application of monolayer or less-layer graphene, graphene film, carbon nanotube/graphene composite film and phase-change polymer/graphene composite materials in the field of thermal management are summarized.

From the early use of mathematical tools to explore the mechanism of neural activity, to the use of artificial neural network models to simulate human intelligence, to the solution of specific problems based on deep networks, AI has developed over the past 80 years and has now entered the era of foundation intelligence (FI), which is characterized by its foothold in large models, serving the broad social groups. The development of large models faces a series of challenges. First, the quality and quantity of data necessary for large models training need to be improved. Second, high-end computing resource is limited, and model training has high power consumption and high carbon emissions, which brings environmental problems. Third, it is the socialization of large models that brings about social development problems such as discrimination and prejudice, the spread of false information, invasion of privacy, and impact on employment. In order to overcome the aforementioned challenges, it is essential to build a federal ecosystem (including federal data, federal control, federal management and federal services) with support of block chain and decentralized autonomous organizations (TRUE+DAO, TAO), and provide solutions for the development of artificial intelligence in the new era.

Integrated development in the new era is an important part of high-quality development. Based on a comprehensive summary of the historical achievements and changes in the planning and construction of high-speed railway stations since the 18th National Congress of the Communist Party of China, this paper focuses on the strategic deployment of building a powerful transportation country, systematically analyzes the interactive mechanism and value orientation of the station-city integration, reveals the basic connotation and mode of the station-city integration. Focusing on the design problems such as the separation of station city space, the lack of urban functions, monotonous environment and low space utilization rate, this paper puts forward the construction strategy of the station-city integration to relieve the station-city development dilemma, reconstruct the order of station-city, release the vitality of city and seek the symbiosis of station-city, providing a solution to promote the high-quality coordinated development of high-speed railway stations and cities.

The application of artificial intelligence(AI) in the military field has recently further improved the overall response ability and execution efficiency of information-based joint operations. Electronic countermeasures combat operations take place in an invisible space, it is more urgent for troops to get AI technology support in a fast-changing electromagnetic situation. By sorting out the main application modes of AI technology in military field, this paper systematically studies the application path of AI in electronic countermeasures from a perspective of operational integrity and puts forward specific thoughts and suggestions for combat command，warfare method application，equipment research and development, and intelligent cooperation, so as to accurately serve the electromagnetic field struggle and improve intelligent combat ability.

Deep space exploration embodies comprehensive national power and has become the commanding height of science and technology competition among the world's space powers. Deep space resource utilization is the key frontier of international deep space exploration,in which the utilization of matter resources is of great significance for humanity's space expansion. This paper introduces the connotation of deep space resource and summarizes the significance of its utilization. Focusing on matter resources, this paper investigates the state-of-the-art research on the volatile extraction and utilization, atmospheric resource utilization, mineral resource extraction and refining, and in-situ manufacturing and construction on planetary surfaces. Finally,this paper offers an outlook for the trends in utilization deep space matter resources, paving the way for the future research in deep space exploration.

At a time of turmoil in the world situation, implementation of scientific system intervention policy is of great significance for effectively dealing with risk challenges. The practice cases of international mission-oriented innovation policy（MOIP）are investigated and compared in terms of of key mission, policy subjects, policy objectives, policy tools and facing up to challenges. It is shown that MOIP has the characteristics of long policy implementation cycle, mission-oriented response to challenges, authority and diversity of policy subjects, multiplicity and specificity of policy objectives, and diversity of policy tools. Suggestions are put forward for China to lay out MOIP, such as strengthening top-level design, scientifically designing strategic direction, strengthening overall coordination, and optimizing and improving policy toolbox.

With the increase of national investment in higher education, the scale and quantity of university laboratoriesm continue to increase, followed by security problems. It is suggested to build an operation and management platform driven by big data, information and digital technology for the production, storage and transportation, procurement, use and recovery of hazardous chemicals to supervise the management and use of hazardous chemicals in colleges and universities.

Osteoarthritis (OA) is a degenerative disease that is prone to occur in the middle-aged and elderly groups. It can erode articular cartilage and its affiliated organization, and seriously affect the life of patients. Hydrogels have good biocompatibility and excellent mechanical properties. Functional hydrogels can make up for the shortcomings of short drug action time and the difficulties to cure OA in common therapy approaches. In this article, we review the recent advances of hydrogel as a carrier to treat osteoarthritis from the aspects of drug treatment of osteoarthritis, cartilage defect repair, and synovial fluid repair. The anti-inflammatory and analgesic mechanism of drug release hydrogel, the mechanism of cartilage repair of cartilage defect repair hydrogel and the joint lubrication mechanism of joint lubrication hydrogel were discussed. On these bases, we also summarize the existing problems and propose further development direction of hydrogel in the treatment of OA.

Blockchain is the key technology for Web 3.0 to build trusted interconnections and value interconnections. As a new decentralized infrastructure, the technology of blockchain is also constantly evolving. Combined with the background of Web 3.0, the technological progress and existing problems of blockchain are introduced in this paper, such as decentralized identity, smart contract, incentive mechanism, and privacy protection. They help to realize the technologies in Web 3.0, such as the data security sharing, business circulation and rights guarantee of users, so as to achieve the goal of more fair distribution and flow of the value.

To understand the development status and problems of sci-tech periodicals in Shandong province, and improve its academic influence, core competitiveness and the ability to serve the overall situation，it is necessary to create a high-level scientific and technological journal phalanx with international communication power and highlighting Shandong characteristics. By distributing questionnaires to 131 sci-tech periodicals and holding seminars, the development status of sci-tech periodicals in Shandong province was investigated in the following five aspects: basic information, composition of human resources, grants and subsidies, business status, and new media development. It was obtained that all of the sci-tech periodicals in Shandong province were small, scattered and weak, being characterized by scattered publishing resources, unbalanced discipline layout, lack of excellent editors, low overall academic influence, and insufficient media-periodicals integration capacity. Suggestions to promote high-quality development of sci-tech periodicals in Shandong province are as follows: optimize the layout of publishing structure, improve the development environment of sci-tech periodicals, strengthen the construction of editors, empower their capacity to publish, promote their cluster construction and promote sci-tech digital transformation.

康复医疗工作是卫生健康事业的重要组成部分。加快推进康复医疗工作发展对全面推进健康中国建设、实施积极应对人口老龄化国家战略、保障和改善民生具有重要意义。

In view of the spectrum planning of China's carrier rocket, the positioning, rocket generation and scale divi-sion of carrier rocket system are put forward, and the focus of carrier rocket type spectrum planning is the third and 3.5 generations of medium and large disposable carrier rockets, as well as the fourth generation of reusable carrier rockets. This paper analyzes the technical development demand and capability development demand of the carrier rockets, and defines the power matching, rocket configuration, launch cost, carrying capacity, payload envelope and launch capacity of the carrier rockets. According to the technical developmen-tal needs and capability needs of the launch vehicles, 7 kinds of launch vehicles of the third generation ex-pendable launch vehicle spectrum, 6 kinds of launch vehicles of the 3.5 generation expendable launch vehicle spectrum, and 2 kinds of launch vehicles of the fourth generation reusable launch vehicle spectrum are pro-posed, respectively. Meanwhile, the evolution and replacement strategy of the second, third, 3.5 and fourth generations are proposed, namely the second launch vehicle is suggested to use until around year 2030, the third launch vehicle is suggested to use until around 2035, and the 3.5 and fourth generation launch vehicles are suggested to use around 2045 when the second and third generation launch vehicles are finally replaced.

Olga Alexandrovna Ladyzhenskaya was one of the most outstanding female mathematical physicists in Russia in the twentieth century, she made outstanding contributions to the field of partial differential equations, especially in hyperbolic, elliptic, parabolic partial differential equations, Navier-Stokes equations, and attractor theory. Her outstanding contributions also made Russia become a scientific and technological power. By explaining her life experience, academic achievements and profound influences, this paper demonstrates her scientific outlook on life, pursuit of scientific excellence and the driving force to promote scientific progress.

China is vigorously building a system of nature reserves with national parks as the main body. However, the protection of national parks and national nature reserves is contrary to international practices. This paper compares and analyzes the differences between China and the United States in terms of national parks and national nature reserves, points out the confusion in concept understanding and management of national parks and national nature reserves in China, and puts forward corresponding suggestions.

The walkability measurement research of subway station area is carried out with the goal of the construction of rail life circle. The walkability influencing factors of rail station area are sorted out, and the walkability measurement system of subway station area is constructed from three aspects: the walkability of the station itself, the walkability of the service facilities in the station area, and the configuration level of the service facilities. Taking 28 track micro centers in Beijing as research objects, this paper uses ArcGIS Spatial analysis method and pedestrian index method to carry out quantitative and qualitative analysis and measurement of the walkability within 1000m of the station area, comprehensively evaluates the road network accessibility and the facilities configuration balance and accessibility in the subway station area, and verifies the matching degree between the measurement results of pedestrian index and the actual dynamic area by thermal map analysis. The current situation of walkability in Beijing track micro center area is pointed out and corresponding countermeasures and suggestions are proposed.

Based on the theoretical and practical background of regional innovation ecosystem, this paper reviews the literature on the concept, research paradigm, evaluation and governance of regional innovation ecosystem. In summary, the research of regional innovation ecosystem in China has gotten some achievements and has achieved many breakthroughs in serving regional economic and social development. In the future, breakthroughs can be made in the following aspects: Firstly, the context of the era background should be expanded. Secondly, the research area and evaluation indicators need to be further enriched and adjusted; Thirdly, the elements of research content should be enriched.

This article summarizes the unique development process of amateur radio under the joint influence of technology policies and folk technology enthusiasts during the Republic of China period, and analyzes the contradiction between the desire of enthusiasts to carry out research smoothly and the government's science and technology policies that were full of skepticism and restrictions. It showcases a historical process during which the active measures taken by enthusiasts solved conflicts. It is concluded that in some special periods, there will be different scientific views between the folk academic circles and the political circles. When contradiction occurs, there will be a complex interaction between the important folk technological enthusiast groups and the government management. The former has the ability to feed back and coordinate against policy obstacles, so as to promote scientific and technological progress. This historical process also shows that only the science and technology policy of encouraging and standardizing can promote the good development of technological enthusiasm.

With its integration into all areas of economy and society, digital technology is exerting a broad and profound impact on human production and life. To promote the construction of first-class science and technology associations, it is required to fully comprehend the key dimensions of digital transformation of science and technology associations, clarify the opportunities and challenges for their future development, and identify the key paths for their transformation and improvement. Based on the experience in planning and construction of platforms such as Smart CAST, Smart CRSTA, and China Volunteers in Science and Technology, the author summarizes and proposes the planning and implementation framework of digital transformation of science and technology associations from five aspects, with a view to facilitating the informatization, digitalization and intellectualization of science and technology associations, and providing optimal services for both science and technology workers and the building of an innovative country.

Large-scale scientific facilities are important equipment for scientific and technological innovations. Since the 18th National Congress of the CPC，construction of large-scale scientific facilities in China has been steadily advanced and many achievements have been acquired. The article reviews the construction and development process of large-scale scientific facilities since the 18th National Congress of the CPC, then analyzes the problems existing in the development of large-scale scientific facilities. Finally, some suggestions are put forward from the aspects of funding investment, solving key technology and strengthening international cooperation for realizing sci-tech self-reliance and self-improvement.

Alzheimer's disease (AD) is a neurodegenerative disease with progressive memory loss and cognitive impairment. Photobiomodulation (PBM) is a promising and innovative therapy for AD treatment. This article reviews the mechanisms of action of PBM for AD treatment and related animal experiments and clinical studies, then analyzes the feasibility, effectiveness, research priorities and challenges of PBM for AD treatment, and finally summarizes the future research trends of PBM for AD treatment, so as to provide a reference for follow-up research.

With more than twenty years of development, China has become a world leader in the core technologies and industrialization of new energy vehicle（NEV） industry. Therefore, it is a great concern to China to ensure the sustainable development of new energy vehicles (NEVs) for the next ten years. This research aims to explore and uncover the laws of certainty from the uncertainty of NEV market, and to analyze and predict the cyclical and structural trend of NEVs' development over the next ten years in China. The main conclusions are as follows: From now to 2026, the market penetration of the NEV will continue to maintain a rapid growth. The new energy revolution, with NEVs, lithium batteries and photovoltaic cells as its three emerging pillars, will make a breakthrough. By 2030, NEVs will achieve profitability. Based on the development of NEVs, the development of new energy will turn into a new energy revolution. By 2035, the priorities of NEVs and the new energy revolution will change from the technological innovation into social concepts and business models reforms. The paper also discussed the possible challenges, including intensified internal competition, overcapacity, market fluctuations and increased uncertainty, which may impede China's NEVs to enter a new level of development, Meanwhile, it proposed feasible solutions to respond to these challenges and risks.

Transformation of scientific and technological achievements is the key to the implementation of "science and technology being the primary productive force", and the core content of the combination of science and technology and economy. Starting from the underlying logic of economic society and scientific and technological innovation, this paper explains the transformation of scientific and technological achievements from the perspective of the integration of innovation chain and industrial chain. On this basis, several major problems existing in the transformation of scientific and technological achievements are deeply analyzed. Finally, to speed up the construction of scientific and technological achievements transformation system and break China's science and technology economy "two skins" problem, corresponding countermeasures and suggestions are put forward in terms of system mechanism, science and technology finance, new research and development institutions, common technology platform, and professional talent system.

In 2023 the development of large generative AI models achieved a series of breakthroughs. This paper reviews the key technologies of large models that have received significant attention, including the emergent abilities of large language model(LLM), development of multimodal LLMs, as well as alignment and knowledge enhancement techniques of large models. The paper also introduces the vertical applications of generative AI in various fields such as healthcare and education, and its role in advancing the development of AI agents and metaverse technologies. Additionally, the challenges and developmental trends in generative AI are discussed, including issues related to data privacy, biased values, copyright disputes, and fake news propagation.

This paper provides an overview of the current development status of hydrogen energy highway transportation, rail transit, shipbuilding, and aviation in China. It analyzes the comprehensive performance of hydrogen fuel cell vehicles in China and points out that the challenges faced by Chinese hydrogen energy vehicles are mainly high costs of vehicles and fuel and insufficient refueling infrastructure. However, as China steps into the middle and late stage of urbanization, heavy-load transportation and special transportation with fixed routes provide opportunities for the development of hydrogen vehicles, and family passenger vehicles will become an important direction. Hydrogen energy rail transit will also play a role in areas where electrification is difficult. Ships and aircraft powered by hydrogen compounds will become the focus of shipbuilding and aviation industries. In the future, hydrogen energy transportation should improve planning, promote technological integration and innovation, develop new hydrogen energy transportation travel modes, build a sound policy system, and adopt carbon market mechanism to achieve a new leap.

This article endeavors to explore the current development status of an all-round and full-cycle health management model for cancer and provide strategic recommendations to address future challenges, in support of the realization of China's ‘Healthy China 2030’strategic plan. Building upon an analysis of the current status of cancer diagnosis, treatment, and prevention and control management in China, the article combines the new trends, missions, and demands in cancer care to propose the developmental trajectory of China's cancer diagnosis and treatment model. This trajectory shifts from a disease-centered multidisciplinary approach to a patient-centered all-round and full-cycle health management at the present stage. This article further delves into the characteristics and shortcomings of the current cancer diagnosis, treatment, and prevention and control system in China, and puts forward corresponding recommendations. These recommendations include enhancing the focus and investment in prevention and screening, standardizing cancer diagnosis and treatment protocols and quality control, prioritizing improvements in patient quality of life, and promoting the development of accessible and intelligent medical services.

With the advantages of safety, economy and environmental friendliness, magnetic confinement fusion energy is an ideal strategic energy for the future and can make a significant contribution to the realization of the "double carbon" goal. Magnetic confinement fusion uses magnetic field to confine and fuse deuterium and tritium fuels in the form of plasma, which is considered to be a promising solution to the energy problem of mankind and a long-term goal for the development of nuclear energy in China. At present, China is actively participating in the construction of the International Thermonuclear Experimental Reactor (ITER), supporting domestic physics and engineering research, and designing the Chinese Fusion Engineering Testing Reactor (CFETR), with the goal of obtaining fusion energy on the basis of absorbing and digesting ITER experience. This article addresses both opportunities and challenges for fusion energy development which is very difficult and requires long-term sustained research.

The green development of China's logistics industry is a key area for the carbon peaking and carbon neutrality goals. This article combines the connotation of green development in the logistics industry to study and construct a green logistics development level indicator system. Based on the carbon emissions inventory and statistical yearbook data of China's provincial-level transportation, logistics, and warehousing industry from 2014 to 2019, factor analysis was used to reduce the dimensionality of green logistics development indicators to form 8 influencing factors. A geographic weighted regression model was applied to explain the provincial differences and spatiotemporal evolution patterns of the driving factors of carbon emissions intensity in China's logistics industry. The study found that during the sample investigation period, the carbon emission intensity of China's logistics industry at the provincial level showed an aggregation phenomenon of weakening year by year, and showed a basic spatial differentiation pattern of "strong in the west and weak in the east". The factor center of gravity showed a trend of shifting from the east to the central region. The factors of extensive logistics development and logistics equipment have the strongest positive effects on carbon emission intensity, while the factors of energy cleanliness, freight structure adjustment, and innovation have inhibitory effects. Based on the analysis results and the resource endowments and development strategies of each province, policy implications for the development of green logistics in China were proposed.

This article provided an overview of current therapeutic strategies to overcome CDK4/6 inhibitor resistance in breast cancer and analyzed the clinical findings of CDK4/6 inhibitor cross-line therapy, novel oral SERDs, PI3K/AKT/mTOR inhibitors, ADC drugs, AURKA inhibitors, HDAC inhibitors, immunotherapeutic strategies and anti-senescence therapies after CDK4/6 inhibitor progression and the related mechanisms. Furthermore, we prospected the potential targets for clinical studies in the future.

Web 3.0 is a frontier issue that deserves attention and involves a number of emerging areas such as the deep integration of human-machine and object networks, virtual-real integration and interaction, diverse business services, intelligent operation and maintenance management, and quantifiable security capabilities. It is difficult for the existing technical architecture to cope with the challenges. However, it is clear that the existing web paradigm is no longer able to support the development of Web 3.0 nor to meet the theoretical dilemma. Based on the fourth paradigm of network technology institutional development and the theory of multimodal network environment, this paper puts forward relevant proposals for building China's next-generation Internet, taking "co-ordinating the relationship between security and development" and achieving quantifiable design and verifiable metrics for network security as one of the key issues and core objectives. On this basis we propose to build an application-driven technology development path and establish an autonomous knowledge system in the field of network technology.