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Yi Wang William, Gaonan LI, Zhe LIU, Xingyu GAO, Hongqiang WANG, Haifeng SONG, Mingli YANG, Yanjing SU, Margulan Ibraimov, Jinshan LI
Envisioning the strategic demands for building a modernized powerful nation in 2040 and motivated by the integrated development of new materials, new productive forces, and emerging industries, this manuscript comprehensively analyzes the common requirements of national strategies, relevant policies, and action outlines regarding frontier-disruptive core technologies and critical material development. Based on the advancement and innovation of Materials Genome Engineering's core technologies setting a crucial foundation for key innovations in AI data infrastructure, foundational material models, R&D of new materials, and industrial applications, AI will further accelerate the development of high-throughput intelligent computing software/tools, drive paradigm shifts from high-throughput experimentation to autonomous experimentation, propel the evolution of material AI agents, construct data resource nodes/platforms with standardized specifications, advance new productivity and novel material industries, as well as foster educational paradigm transformation and next-generation talent cultivation. The convergence of Materials Genome Engineering and intelligent science is fundamentally reshaping the underlying logic of material science, technology, and education through a trinity model consisted of ''theoretical reconstruction, technological empowerment, and industrial traction''. This integration represents not merely disciplinary upgrading, but a systematic transformation encompassing scientific paradigms, industrial ecosystems, and talent development models. It will cultivate interdisciplinary professionals crucial for strategic fields such as advanced materials, emerging industries, and future-oriented sectors.