In 2016, scientific workers presented lots of descriptive reviews and constructive suggestions. In this article, some important "sounds" are selected aiming at the hot topics about science and technology such as gravitational wave, gene transfer, the dark matter particle explorer named Wukong, quantum communications satellite nicknamed Micius, and so on. The "sounds" consists of 5 topics:scientific and technological innovation, basic research, big data, artificial intelligence and gene transfer, in which the basic research includes 4 parts of gravitational wave, dark matter, quantum technology and collider.